WormBase Tree Display for Gene: WBGene00020022
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| WBGene00020022 | SMap | S_parent | Sequence | R12C12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | gldc-1 | Person_evidence | WBPerson151 | |||||
| Sequence_name | R12C12.1 | ||||||||
| Molecular_name | R12C12.1a | ||||||||
| R12C12.1a.1 | |||||||||
| CE02846 | |||||||||
| R12C12.1b | |||||||||
| CE51882 | |||||||||
| R12C12.1b.1 | |||||||||
| Other_name | CELE_R12C12.1 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | gldc-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 29 Nov 2016 11:06:21 | WBPerson2970 | Name_change | CGC_name | gldc-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gldc | ||||||||
| Allele (47) | |||||||||
| Strain | WBStrain00002788 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | R12C12.1 is orthologous to human GLYCINE DECARBOXYLASE (GLDC; OMIM:238300), which when mutated leads to glycine encephalopathy. | Curator_confirmed | WBPerson1823 | |||||
| WBPerson567 | |||||||||
| Date_last_updated | 06 Aug 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable glycine binding activity; glycine dehydrogenase (decarboxylating) activity; and pyridoxal phosphate binding activity. Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be located in mitochondrion. Predicted to be part of glycine cleavage complex. Expressed in head. Human ortholog(s) of this gene implicated in glycine encephalopathy and stomach cancer. Is an ortholog of human GLDC (glycine decarboxylase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9268 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4313) | ||||
| DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4313) | ||||||
| Molecular_info | Corresponding_CDS | R12C12.1a | |||||||
| R12C12.1b | |||||||||
| Corresponding_CDS_history | R12C12.1b:wp257 | ||||||||
| Corresponding_transcript | R12C12.1a.1 | ||||||||
| R12C12.1b.1 | |||||||||
| Other_sequence (56) | |||||||||
| Associated_feature | WBsf644252 | ||||||||
| WBsf221387 | |||||||||
| WBsf221388 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00051835 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00017790 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00034881 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1611 | ||||||||
| Chronogram1837 | |||||||||
| Expr6514 | |||||||||
| Expr1014781 | |||||||||
| Expr1038698 | |||||||||
| Expr1155495 | |||||||||
| Expr2012090 | |||||||||
| Expr2030326 | |||||||||
| Drives_construct | WBCnstr00003315 | ||||||||
| WBCnstr00025426 | |||||||||
| Construct_product | WBCnstr00025426 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (252) | |||||||||
| Interaction (92) | |||||||||
| Map_info | Positive | Positive_clone | R12C12 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | II | -0.596716 | |||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
