WormBase Tree Display for Gene: WBGene00019967

WBGene00019967 SMap: S_parent: Sequence: R08F11
  Identity: Version: 2
    Name: CGC_name: cyp-33C8
      Sequence_name: R08F11.3
      Molecular_name: R08F11.3
        R08F11.3.1
        CE12584
      Other_name: CELE_R08F11.3 Accession_evidence: NDB BX284605
      Public_name: cyp-33C8
    DB_info: Database: AceView gene 5E272
        WormQTL gene WBGene00019967
        WormFlux gene WBGene00019967
        NDB locus_tag CELE_R08F11.3
        Panther gene CAEEL|WormBase=WBGene00019967|UniProtKB=O02641
          family PTHR24300
        NCBI gene 187705
        RefSeq protein NM_071650.7
        TrEMBL UniProtAcc O02641
        UniProt_GCRP UniProtAcc O02641
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 21 Sep 2004 09:38:16 WBPerson1971 Name_change: CGC_name: cyp-33C8
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cyp
    Allele (53)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (134)
    Paralog (44)
    Structured_description: Automated_description: Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:783 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2622)
      DOID:1073 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2622)
  Molecular_info: Corresponding_CDS: R08F11.3
    Corresponding_transcript: R08F11.3.1
    Other_sequence: FC549891.1
      ACC23062_1
      FC548150.1
      XIC02276_1
      Tcir_isotig20566
      MI03585
      XI02955
      MH09037
      BXC02674_1
    Associated_feature: WBsf652548
      WBsf981918
      WBsf999690
      WBsf233528
  Experimental_info: RNAi_result: WBRNAi00092662 Inferred_automatically: RNAi_primary
      WBRNAi00051558 Inferred_automatically: RNAi_primary
      WBRNAi00017598 Inferred_automatically: RNAi_primary
      WBRNAi00034755 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1011139
      Expr1155236
      Expr2010719
      Expr2028957
    Drives_construct: WBCnstr00025460
    Construct_product: WBCnstr00025460
    Microarray_results (18)
    Expression_cluster (354)
    Interaction (42)
  Map_info: Map: V Position: -7.99046 Error: 0.000812
    Positive: Positive_clone: R08F11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031529
    WBPaper00038491
    WBPaper00042257
    WBPaper00049920
    WBPaper00055090
    WBPaper00060760
    WBPaper00065331
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene