WormBase Tree Display for Gene: WBGene00019476

WBGene00019476 SMap: S_parent: Sequence: K07C11
  Identity: Version: 2
    Name: CGC_name: timp-1 Person_evidence: WBPerson2644
      Sequence_name: K07C11.3
      Molecular_name: K07C11.3
        K07C11.3.1
        CE29510
      Other_name: CELE_K07C11.3 Accession_evidence: NDB BX284605
      Public_name: timp-1
    DB_info: Database: AceView gene 5I687
        WormQTL gene WBGene00019476
        WormFlux gene WBGene00019476
        NDB locus_tag CELE_K07C11.3
        Panther gene CAEEL|WormBase=WBGene00019476|UniProtKB=Q21267
          family PTHR11844
        NCBI gene 179199
        RefSeq protein NM_072714.8
        TREEFAM TREEFAM_ID TF317409
        TrEMBL UniProtAcc Q21267
        UniProt_GCRP UniProtAcc Q21267
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 05 Sep 2017 13:25:30 WBPerson2970 Name_change: CGC_name: timp-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: timp
    Allele (15)
    Strain: WBStrain00051251
    RNASeq_FPKM (74)
    GO_annotation: 00071022
      00071023
      00071024
      00071025
      00071026
      00071027
      00071028
      00124320
    Ortholog (27)
    Paralog: WBGene00019478 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of membrane protein ectodomain proteolysis and response to organic substance. Predicted to be located in extracellular matrix and extracellular space. Expressed in several structures, including coelomocyte; gonad; head neurons; nerve ring; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Duchenne muscular dystrophy; Huntington's disease; artery disease (multiple); and carcinoma (multiple). Is an ortholog of human TIMP2 (TIMP metallopeptidase inhibitor 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (16)
  Molecular_info: Corresponding_CDS: K07C11.3
    Corresponding_transcript: K07C11.3.1
    Other_sequence: CJC14055_1
    Associated_feature: WBsf646992
      WBsf232076
  Experimental_info: RNAi_result: WBRNAi00050122 Inferred_automatically: RNAi_primary
      WBRNAi00034052 Inferred_automatically: RNAi_primary
      WBRNAi00016701 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14699
      Expr14701
      Expr1012009
      Expr1038413
      Expr1153823
      Expr2004845
      Expr2023066
    Drives_construct: WBCnstr00025812
      WBCnstr00040773
      WBCnstr00040776
    Construct_product: WBCnstr00025812
      WBCnstr00040773
    Microarray_results (20)
    Expression_cluster (157)
    Interaction (125)
  Map_info: Map: V Position: 1.20444
    Positive: Positive_clone: K07C11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00056623
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene