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WormBase Tree Display for Gene: WBGene00018743

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Name Class

WBGene00018743SMapS_parentSequenceF53B3
IdentityVersion1
NameSequence_nameF53B3.5
Molecular_nameF53B3.5
F53B3.5.1
CE53648
Other_nameCELE_F53B3.5Accession_evidenceNDBBX284606
Public_nameF53B3.5
DB_infoDatabaseAceViewgeneXD492
WormQTLgeneWBGene00018743
WormFluxgeneWBGene00018743
NDBlocus_tagCELE_F53B3.5
PanthergeneCAEEL|WormBase=WBGene00018743|UniProtKB=Q20713
familyPTHR21215
NCBIgene180578
RefSeqproteinNM_076098.9
TREEFAMTREEFAM_IDTF312994
TrEMBLUniProtAccQ20713
UniProt_GCRPUniProtAccQ20713
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:00WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (99)
StrainWBStrain00033199
RNASeq_FPKM (74)
GO_annotation00068860
00123781
Ortholog (32)
Structured_descriptionConcise_descriptionF53B3.5 encodes a claudin homolog that may regulate ion channels; F53B3.5 is distantly similar to mammalian voltage-dependent calcium channel gamma subunits that are known or suspected to prevent epilepsy in vivo (e.g., stargazin; MGI:1316660); F53B3.5 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.Paper_evidenceWBPaper00004961
WBPaper00005654
WBPaper00005946
WBPaper00005975
WBPaper00012762
WBPaper00012856
WBPaper00012941
WBPaper00013626
WBPaper00018356
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be located in membrane.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF53B3.5
Corresponding_CDS_historyF53B3.5:wp230
F53B3.5:wp272
Corresponding_transcriptF53B3.5.1
Other_sequence (12)
Associated_feature (21)
Experimental_infoRNAi_resultWBRNAi00094877Inferred_automaticallyRNAi_primary
WBRNAi00015483Inferred_automaticallyRNAi_primary
WBRNAi00048085Inferred_automaticallyRNAi_primary
WBRNAi00033498Inferred_automaticallyRNAi_primary
WBRNAi00015482Inferred_automaticallyRNAi_primary
Expr_patternExpr1014430
Expr1038071
Expr1151895
Expr2004038
Expr2022261
Microarray_results (22)
Expression_cluster (259)
Interaction (94)
Map_infoPositivePositive_cloneF53B3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionX-12.6849
MethodGene