WormBase Tree Display for Gene: WBGene00017241
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WBGene00017241 | SMap | S_parent | Sequence | F08C6 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | pcyt-1 | Person_evidence | WBPerson1711 | |||||
Sequence_name | F08C6.2 | ||||||||
Molecular_name | F08C6.2a | ||||||||
F08C6.2a.1 | |||||||||
CE30937 | |||||||||
F08C6.2b | |||||||||
CE39144 | |||||||||
F08C6.2b.1 | |||||||||
Other_name | CELE_F08C6.2 | Accession_evidence | NDB | BX284606 | |||||
Public_name | pcyt-1 | ||||||||
DB_info | Database (14) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 20 Apr 2011 10:05:24 | WBPerson2970 | Name_change | CGC_name | pcyt-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | pcyt | ||||||||
Allele (156) | |||||||||
Strain | WBStrain00031168 | ||||||||
WBStrain00037474 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (42) | |||||||||
Paralog | WBGene00017878 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
WBGene00021215 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00016531 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00021352 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | pcyt-1 encodes a lipid-activated CTP:phosphocholine cytidylyltransferase (CCT), with CCT activity in vitro; recombinant PCYT-1 is most activated by a 1:1 mixture of phosphatidylcholine:oleate vesicles; an inhibitory 21-residue segment (residues 246-266) is critical for specific activation of PCYT-1 by lipids, since deletion or mutation of this segment causes PCYT-1 to be constitutively active without its normal lipid substrate. | Paper_evidence | WBPaper00004651 | |||||
WBPaper00004877 | |||||||||
WBPaper00005654 | |||||||||
WBPaper00035321 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 14 Oct 2011 00:00:00 | ||||||||
Automated_description | Enables choline-phosphate cytidylyltransferase activity. Involved in phosphatidylcholine biosynthetic process. Expressed in head. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia with cone-rod dystrophy. Is an ortholog of human PCYT1A (phosphate cytidylyltransferase 1A, choline) and PCYT1B (phosphate cytidylyltransferase 1B, choline). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0112300 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8754) | ||||
Molecular_info | Corresponding_CDS | F08C6.2a | |||||||
F08C6.2b | |||||||||
Corresponding_CDS_history | F08C6.2:wp149 | ||||||||
Corresponding_transcript | F08C6.2a.1 | ||||||||
F08C6.2b.1 | |||||||||
Other_sequence (77) | |||||||||
Associated_feature (20) | |||||||||
Experimental_info | RNAi_result (34) | ||||||||
Expr_pattern | Chronogram1664 | ||||||||
Expr5678 | |||||||||
Expr1019705 | |||||||||
Expr1037403 | |||||||||
Expr1147952 | |||||||||
Expr2014791 | |||||||||
Expr2033025 | |||||||||
Drives_construct | WBCnstr00002991 | ||||||||
WBCnstr00027460 | |||||||||
Construct_product | WBCnstr00027460 | ||||||||
Microarray_results (25) | |||||||||
Expression_cluster (177) | |||||||||
Interaction (73) | |||||||||
Map_info | Map | X | Position | -1.49196 | |||||
Positive | Positive_clone | F08C6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (16) | |||||||||
Picture | WBPicture0000013096 | ||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |