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WormBase Tree Display for Gene: WBGene00016943

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Name Class

WBGene00016943SMapS_parentSequenceC55B7
IdentityVersion2
NameCGC_nameacdh-1
Sequence_nameC55B7.4
Molecular_nameC55B7.4a
C55B7.4a.1
CE09015
C55B7.4b
CE32840
C55B7.4b.1
C55B7.4b.2
Other_namedod-12
CELE_C55B7.4Accession_evidenceNDBBX284601
Public_nameacdh-1
DB_infoDatabaseAceViewgene1H75
WormQTLgeneWBGene00016943
WormFluxgeneWBGene00016943
NDBlocus_tagCELE_C55B7.4
PanthergeneCAEEL|WormBase=WBGene00016943|UniProtKB=H2KZG6
familyPTHR43884
NCBIgene172358
RefSeqproteinNM_001383261.2
NM_001380557.1
TREEFAMTREEFAM_IDTF105055
TrEMBLUniProtAccH2KZG6
Q8IAB6
UniProt_GCRPUniProtAccH2KZG6
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
225 Aug 2004 14:33:45WBPerson1971Name_changeCGC_nameacdh-1
Other_namedod-12
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classacdh
Allele (22)
StrainWBStrain00032056
WBStrain00036246
WBStrain00036314
RNASeq_FPKM (74)
GO_annotation00022255
00022256
00022257
00022258
00022259
00022260
00122446
00122447
Contained_in_operonCEOP1907
Ortholog (38)
Paralog (22)
Structured_descriptionConcise_descriptionacdh-1 encodes a short-chain acyl-CoA dehydrogenase; ACDH-1 is predicted to be a mitochondrial enzyme that catalyzes the first step of fatty acid beta-oxidation and thus plays a key role in energy production; steady-state acdh-1 mRNA levels are under the control of the MDT-15 mediator complex subunit; in addition, gene expression studies indicate that acdh-1 expression is upregulated in daf-2 mutant animals, but downregulated in fasted animals; loss of acdh-1 activity via RNAi can shorten lifespan.Paper_evidenceWBPaper00005976
WBPaper00026800
WBPaper00027365
Curator_confirmedWBPerson1843
Date_last_updated10 Aug 2006 00:00:00
Automated_descriptionPredicted to enable acyl-CoA dehydrogenase activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in mitochondrion. Expressed in E lineage cell; hypodermis; and neurons. Is an ortholog of human ACADSB (acyl-CoA dehydrogenase short/branched chain).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC55B7.4a
C55B7.4b
Corresponding_transcriptC55B7.4a.1
C55B7.4b.1
C55B7.4b.2
Other_sequence (19)
Associated_featureWBsf643373
WBsf643374
WBsf978997
WBsf217836
WBsf217837
WBsf217838
WBsf217839
WBsf217840
Experimental_infoRNAi_result (14)
Expr_patternExpr9109
Expr13237
Expr15754
Expr15906
Expr1025163
Expr1037269
Expr1147209
Expr2009132
Expr2027369
Drives_constructWBCnstr00006161
WBCnstr00013727
WBCnstr00017529
WBCnstr00017596
WBCnstr00027688
Construct_productWBCnstr00027688
Microarray_results (34)
Expression_cluster (410)
Interaction (112)
Map_infoMapIPosition1.16367Error0.004812
PositivePositive_cloneC55B7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5183
4359
5614
Pseudo_map_position
Reference (38)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene