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WormBase Tree Display for Gene: WBGene00016408

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Name Class

WBGene00016408SMapS_parentSequenceC34E10
IdentityVersion3
NameCGC_nameprmt-5Person_evidenceWBPerson4055
Sequence_nameC34E10.5
Molecular_nameC34E10.5
C34E10.5.1
CE29033
C34E10.5.2
C34E10.5.3
Other_nametag-251Person_evidenceWBPerson201
CELE_C34E10.5Accession_evidenceNDBBX284603
Public_nameprmt-5
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
220 Jul 2007 11:50:19WBPerson2970Name_changeCGC_nameprmt-5
320 Jul 2007 11:50:19WBPerson2970Name_changeOther_nametag-251
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classprmt
Allele (48)
StrainWBStrain00036097
RNASeq_FPKM (74)
GO_annotation (42)
Contained_in_operonCEOP3268
Ortholog (36)
Structured_descriptionAutomated_descriptionEnables DNA-binding transcription factor binding activity; p53 binding activity; and protein methyltransferase activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of DNA damage response, signal transduction by p53 class mediator; and response to odorant. Located in nucleus. Human ortholog(s) of this gene implicated in Leydig cell tumor and seminoma. Is an ortholog of human PRMT5 (protein arginine methyltransferase 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:2696Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10894)
DOID:4440Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10894)
Molecular_infoCorresponding_CDSC34E10.5
Corresponding_transcriptC34E10.5.1
C34E10.5.2
C34E10.5.3
Other_sequence (21)
Associated_featureWBsf658920
WBsf224888
Experimental_infoRNAi_result (15)
Expr_patternExpr1018696
Expr1037030
Expr1145902
Expr2015099
Expr2033337
Drives_constructWBCnstr00028094
Construct_productWBCnstr00028094
AntibodyWBAntibody00002111
Microarray_results (22)
Expression_cluster (88)
Interaction (111)
Map_infoMapIIIPosition-1.87136Error0.010434
PositivePositive_cloneC34E10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5207
4167
Pseudo_map_position
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene