WormBase Tree Display for Gene: WBGene00015802

WBGene00015802 SMap: S_parent: Sequence: C15H9
  Identity: Version: 4
    Name: CGC_name: kynu-1 Person_evidence: WBPerson8783
      Sequence_name: C15H9.7
      Molecular_name: C15H9.7
        C15H9.7.1
        CE06835
      Other_name: XG726 Accession_evidence: EMBL AF303267
        flu-2 Person_evidence: WBPerson1519
            WBPerson2582
            WBPerson34
        CELE_C15H9.7 Accession_evidence: NDB BX284606
      Public_name: kynu-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 31 Aug 2012 11:56:39 WBPerson2970 Name_change: CGC_name: flu-2
        3 10 Jun 2014 12:12:12 WBPerson1983 Event: Acquires_merge: WBGene00001472
        4 19 Feb 2016 16:48:22 WBPerson2970 Name_change: CGC_name: kynu-1
                Other_name: flu-2
      Acquires_merge: WBGene00001472
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: kynu
    Reference_allele: WBVar00143675
    Allele (43)
    Legacy_information: e1003 : reduced gut fluorescence dull green; high orthoaminophenol content low kynureninase levels enhanced mutagen sensitivity. ES1. ME3. NA5.
      See also e1003
      [C.elegansII] e1003 : reduced gut fluorescence dull green; high orthoaminophenol content low kynureninase levels enhanced mutagen sensitivity. ES1. ME3. OA4. [Babu 1974; Bhat and Babu 1980]
    Strain: WBStrain00035117
      WBStrain00004224
      WBStrain00030535
    RNASeq_FPKM (74)
    GO_annotation (25)
    Ortholog (36)
    Structured_description: Automated_description: Predicted to enable kynureninase activity. Predicted to be involved in anthranilate metabolic process and tryptophan catabolic process to kynurenine. Predicted to be located in cytoplasm. Expressed in E lineage cell and hypodermal cell. Human ortholog(s) of this gene implicated in hydroxykynureninuria. Is an ortholog of human KYNU (kynureninase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112257 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6469)
      EFO:MONDO:0020831 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6469)
  Molecular_info: Corresponding_CDS: C15H9.7
    Corresponding_transcript: C15H9.7.1
    Other_sequence (38)
    Associated_feature: WBsf654043
      WBsf654044
      WBsf237440
  Experimental_info: RNAi_result: WBRNAi00010805 Inferred_automatically: RNAi_primary
      WBRNAi00040638 Inferred_automatically: RNAi_primary
      WBRNAi00023052 Inferred_automatically: RNAi_primary
      WBRNAi00033520 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14797
      Expr14798
      Expr14799
      Expr1028880
      Expr1036763
      Expr1144692
      Expr2012990
      Expr2031222
    Drives_construct: WBCnstr00028554
      WBCnstr00041426
    Construct_product: WBCnstr00028554
      WBCnstr00041426
    Microarray_results (19)
    Expression_cluster (239)
    Interaction (110)
  Map_info: Positive: Positive_clone: C15H9 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 289
      Multi_point: 955
        1858
      Pos_neg_data: 5500
        8418
    Interpolated_map_position: X -3.70922
  Reference (24)
  Remark: [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag.
  Method: Gene