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WormBase Tree Display for Gene: WBGene00013643

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Name Class

WBGene00013643SMapS_parentSequenceY105C5A
IdentityVersion1
NameSequence_nameY105C5A.24
Molecular_nameY105C5A.24
Y105C5A.24.1
CE36218
Other_nameCELE_Y105C5A.24Accession_evidenceNDBBX284604
Public_nameY105C5A.24
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:55WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (84)
RNASeq_FPKM (74)
GO_annotation (32)
Ortholog (25)
Paralog (13)
Structured_descriptionAutomated_descriptionPredicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including autophagy; axon extension; and positive regulation of autophagy. Predicted to be located in autophagosome; cytosol; and phagophore assembly site membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); frontometaphyseal dysplasia 2; and intrinsic cardiomyopathy (multiple). Is an ortholog of human MAP3K7 (mitogen-activated protein kinase kinase kinase 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111785Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6859)
DOID:11520Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6859)
DOID:10283Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6859)
DOID:11984Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6859)
DOID:0111787Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6859)
DOID:12930Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6859)
DOID:3393Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6859)
Molecular_infoCorresponding_CDSY105C5A.24
Corresponding_CDS_historyY105C5A.24:wp114
Corresponding_transcriptY105C5A.24.1
Other_sequenceOden_isotig05394
ACC13097_1
Oden_isotig05392
Oden_isotig05395
EX563505.1
Oden_isotig05396
Oden_isotig05393
Oden_isotig05391
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00112980Inferred_automaticallyRNAi_primary
WBRNAi00019848Inferred_automaticallyRNAi_primary
WBRNAi00055181Inferred_automaticallyRNAi_primary
WBRNAi00113210Inferred_automaticallyRNAi_primary
WBRNAi00036464Inferred_automaticallyRNAi_primary
Expr_patternExpr1022564
Expr1036096
Expr1158714
Expr2006945
Expr2025171
Drives_constructWBCnstr00029576
Construct_productWBCnstr00029576
Microarray_results (18)
Expression_cluster (120)
Interaction (27)
Map_infoPositivePositive_cloneY105C5AInferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIV14.4082
ReferenceWBPaper00024295
WBPaper00038491
WBPaper00055090
WBPaper00065331
MethodGene