WormBase Tree Display for Gene: WBGene00013038
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| WBGene00013038 | SMap | S_parent | Sequence | Y49E10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | ani-1 | Person_evidence | WBPerson1816 | |||||
| WBPerson1836 | |||||||||
| Sequence_name | Y49E10.19 | ||||||||
| Molecular_name | Y49E10.19 | ||||||||
| Y49E10.19.1 | |||||||||
| CE33878 | |||||||||
| Y49E10.19.2 | |||||||||
| Other_name | CELE_Y49E10.19 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | ani-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 15 Nov 2004 11:05:03 | WBPerson2970 | Name_change | CGC_name | ani-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ani | ||||||||
| Allele (163) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (40) | |||||||||
| Contained_in_operon | CEOP3798 | ||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00007409 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00012835 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00019608 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ani-1 encodes one of three C. elegans anillins; ANI-1 activity is required in the early embryo for cortical contractile events, including polar body extrusion, membrane ruffling, and pseudocleavage; at later stages of development, ANI-1 also plays a role in cuticle formation, coordinated locomotion, vulval development, and male tail formation; in regulating cortical events, ANI-1 appears to function by positively regulating septin (UNC-59 and UNC-61) localization to the contractile ring as well as formation of septin- and NMY-2-containing cortical patches; in telophase embryos, ANI-1 localizes to the cell cortex and cleavage furrow. | Paper_evidence | WBPaper00025229 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 15 Nov 2007 00:00:00 | ||||||||
| Automated_description | Enables actin filament binding activity; microtubule binding activity; and small GTPase binding activity. Involved in several processes, including first cell cycle pseudocleavage; nematode male tail tip morphogenesis; and organelle organization. Located in several cellular components, including cleavage furrow; growth cone; and midbody. Expressed in several structures, including QL.a; QL.pa; germ line; neuroblasts; and neurons. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Is an ortholog of human ANLN (anillin, actin binding protein). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111133 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14082) | ||||
| Molecular_info | Corresponding_CDS | Y49E10.19 | |||||||
| Corresponding_CDS_history | Y49E10.19:wp99 | ||||||||
| Corresponding_transcript | Y49E10.19.1 | ||||||||
| Y49E10.19.2 | |||||||||
| Other_sequence (21) | |||||||||
| Associated_feature | WBsf651542 | ||||||||
| WBsf651543 | |||||||||
| WBsf994647 | |||||||||
| WBsf994648 | |||||||||
| WBsf1016201 | |||||||||
| WBsf1016202 | |||||||||
| WBsf227667 | |||||||||
| WBsf227668 | |||||||||
| Experimental_info | RNAi_result (22) | ||||||||
| Expr_pattern | Expr3283 | ||||||||
| Expr11252 | |||||||||
| Expr12269 | |||||||||
| Expr14312 | |||||||||
| Expr1016866 | |||||||||
| Expr1035795 | |||||||||
| Expr1160457 | |||||||||
| Expr2009335 | |||||||||
| Expr2027571 | |||||||||
| Drives_construct | WBCnstr00040016 | ||||||||
| Construct_product | WBCnstr00005647 | ||||||||
| WBCnstr00008813 | |||||||||
| WBCnstr00008814 | |||||||||
| WBCnstr00014920 | |||||||||
| WBCnstr00020556 | |||||||||
| WBCnstr00040016 | |||||||||
| Antibody | WBAntibody00000927 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (181) | |||||||||
| Interaction (117) | |||||||||
| Map_info | Map | III | Position | 17.8747 | Error | 0.015814 | |||
| Positive | Positive_clone | Y49E10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (34) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
