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WormBase Tree Display for Gene: WBGene00012148

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Name Class

WBGene00012148SMapS_parentSequenceCHROMOSOME_II
IdentityVersion2
NameCGC_nameinos-1Person_evidenceWBPerson9275
Sequence_nameVF13D12L.1
Molecular_nameVF13D12L.1
VF13D12L.1.1
CE31076
Other_nameCELE_VF13D12L.1Accession_evidenceNDBBX284602
Public_nameinos-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
205 May 2011 12:15:34WBPerson2970Name_changeCGC_nameinos-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classinos
Allele (39)
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (36)
Structured_descriptionConcise_descriptioninos-1 encodes the C. elegans myo-inositol-1-phosphate (MIP) synthase ortholog; by homology, the product of inos-1 is predicted to function in de novo inositol biosynthesis by catalyzing the conversion of glucose-6-phosphate to inositol-1-phosphate; loss of inos-1 activity via RNAi has been reported to result in low levels of embryonic lethality, larval lethality, slow growth, uncoordinated locomotion, and a substantial increase in fat content; loss of inos-1 activity also results in a slight increase in the variability of the defecation cycle length, although this increase is not statistically significant; in situ hybridization studies reveal that inos-1 mRNA is expressed faintly in the germline.Paper_evidenceWBPaper00005654
WBPaper00005655
WBPaper00006395
WBPaper00025054
WBPaper00027758
WBPaper00031535
Curator_confirmedWBPerson1843
Date_last_updated05 May 2011 00:00:00
Automated_descriptionPredicted to enable inositol-3-phosphate synthase activity. Predicted to be involved in inositol biosynthetic process. Predicted to be located in cytoplasm. Expressed in germ line. Is an ortholog of human ISYNA1 (inositol-3-phosphate synthase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSVF13D12L.1
Corresponding_transcriptVF13D12L.1.1
Other_sequence (81)
Associated_featureWBsf650614
WBsf650615
WBsf650616
WBsf666190
WBsf666191
WBsf989857
WBsf223984
Experimental_infoRNAi_resultWBRNAi00009234Inferred_automaticallyRNAi_primary
WBRNAi00024196Inferred_automaticallyRNAi_primary
WBRNAi00033587Inferred_automaticallyRNAi_primary
WBRNAi00076726Inferred_automaticallyRNAi_primary
WBRNAi00026432Inferred_automaticallyRNAi_primary
WBRNAi00054466Inferred_automaticallyRNAi_primary
WBRNAi00054465Inferred_automaticallyRNAi_primary
WBRNAi00077806Inferred_automaticallyRNAi_primary
Expr_patternExpr4091
Expr1023077
Expr1035373
Expr1158012
Expr2012744
Expr2030981
Drives_constructWBCnstr00030104
Construct_productWBCnstr00030104
Microarray_results (19)
Expression_cluster (148)
Interaction (76)
Map_infoMapIIPosition3.99091Error0.005099
PositivePositive_cloneVF13D12LInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00019539
WBPaper00031535
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene