WormBase Tree Display for Gene: WBGene00012005
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WBGene00012005 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 4 | |||||||
Name | CGC_name | jun-1 | Person_evidence | WBPerson2962 | |||||
WBPerson443 | |||||||||
Sequence_name | T24H10.7 | ||||||||
Molecular_name (27) | |||||||||
Other_name | CELE_T24H10.7 | Accession_evidence | NDB | BX284602 | |||||
Public_name | jun-1 | ||||||||
DB_info | Database | AceView | gene | 2J421 | |||||
WormQTL | gene | WBGene00012005 | |||||||
WormFlux | gene | WBGene00012005 | |||||||
NDB | locus_tag | CELE_T24H10.7 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00012005|UniProtKB=G5ECU7 | |||||||
family | PTHR11462 | ||||||||
NCBI | gene | 174452 | |||||||
RefSeq | protein | NM_001356878.3 | |||||||
NM_001356880.3 | |||||||||
NM_001136355.4 | |||||||||
NM_001356881.3 | |||||||||
NM_001383910.2 | |||||||||
NM_001356879.3 | |||||||||
NM_001027195.4 | |||||||||
NM_001027197.5 | |||||||||
NM_001027196.5 | |||||||||
SwissProt | UniProtAcc | G5ECU7 | |||||||
TrEMBL | UniProtAcc | A0A2C9C3K0 | |||||||
A0A2C9C3E7 | |||||||||
A0A2C9C2T0 | |||||||||
A0A2C9C2Y8 | |||||||||
UniProt_GCRP | UniProtAcc | G5ECU7 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 29 Nov 2004 12:57:28 | WBPerson1983 | Event | Acquires_merge | WBGene00012001 | ||||
3 | 27 Apr 2007 10:10:56 | WBPerson1983 | Event | Acquires_merge | WBGene00012006 | ||||
4 | 07 Nov 2007 09:36:21 | WBPerson2970 | Name_change | CGC_name | jun-1 | ||||
Acquires_merge | WBGene00012001 | ||||||||
WBGene00012006 | |||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | jun | ||||||||
Allele (304) | |||||||||
Strain | WBStrain00036395 | ||||||||
WBStrain00036410 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (28) | |||||||||
Contained_in_operon | CEOP2709 | ||||||||
Ortholog (31) | |||||||||
Structured_description | Concise_description | jun-1 encodes a basic-leucine zipper (bZIP) transcription factor that is the C. elegans JUN homolog; jun-1 activity is essential for regulation of ovulation, and thus normal levels of fertility; in regulating ovulation, JUN-1 functions with FOS-1 to regulate expression of plc-1 which encodes a phospholipase C essential for IP3 production and ovulation; in addition, JUN-1 interacts with FOS-1 in vitro to form heterodimers capable of binding upstream regulatory sequences of egl-13, which encodes a transcription factor required for uterine cell fate specification; jun-1 is expressed in the uterus and the spermatheca. | Paper_evidence | WBPaper00031111 | |||||
WBPaper00034689 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 19 Jan 2010 00:00:00 | ||||||||
Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of RNA splicing; and response to starvation. Located in nucleus. Expressed in several structures, including excretory cell; hermaphrodite gonad; nervous system; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and lymphoma (multiple). Is an ortholog of human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); JUNB (JunB proto-oncogene, AP-1 transcription factor subunit); and JUND (JunD proto-oncogene, AP-1 transcription factor subunit). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (22) | ||||||||
Molecular_info | Corresponding_CDS | T24H10.7a | |||||||
T24H10.7b | |||||||||
T24H10.7c | |||||||||
T24H10.7d | |||||||||
T24H10.7e | |||||||||
T24H10.7f | |||||||||
T24H10.7g | |||||||||
T24H10.7h | |||||||||
T24H10.7i | |||||||||
Corresponding_CDS_history | T24H10.7:wp136 | ||||||||
Corresponding_transcript | T24H10.7a.1 | ||||||||
T24H10.7b.1 | |||||||||
T24H10.7c.1 | |||||||||
T24H10.7d.1 | |||||||||
T24H10.7e.1 | |||||||||
T24H10.7f.1 | |||||||||
T24H10.7g.1 | |||||||||
T24H10.7h.1 | |||||||||
T24H10.7i.1 | |||||||||
Other_sequence (42) | |||||||||
Associated_feature (34) | |||||||||
Gene_product_binds (375) | |||||||||
Transcription_factor | WBTranscriptionFactor000109 | ||||||||
WBTranscriptionFactor000501 | |||||||||
Experimental_info | RNAi_result (33) | ||||||||
Expr_pattern (14) | |||||||||
Drives_construct | WBCnstr00012826 | ||||||||
WBCnstr00014260 | |||||||||
WBCnstr00014283 | |||||||||
WBCnstr00014284 | |||||||||
WBCnstr00014288 | |||||||||
WBCnstr00014300 | |||||||||
WBCnstr00014302 | |||||||||
WBCnstr00030207 | |||||||||
Construct_product | WBCnstr00030207 | ||||||||
Microarray_results (48) | |||||||||
Expression_cluster (184) | |||||||||
Interaction (46) | |||||||||
Map_info | Map | II | Position | 1.04759 | Error | 0.001496 | |||
Positive | Positive_clone | T24H10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (24) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |