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WormBase Tree Display for Gene: WBGene00011699

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Name Class

WBGene00011699SMapS_parentSequenceT10H4
IdentityVersion2
NameCGC_namecyp-34A2
Sequence_nameT10H4.11
Molecular_nameT10H4.11
T10H4.11.1
CE16396
Other_nameCELE_T10H4.11Accession_evidenceNDBBX284605
Public_namecyp-34A2
DB_infoDatabaseAceViewgene5P764
WormQTLgeneWBGene00011699
WormFluxgeneWBGene00011699
NDBlocus_tagCELE_T10H4.11
PanthergeneCAEEL|WormBase=WBGene00011699|UniProtKB=O62377
familyPTHR24300
NCBIgene188400
RefSeqproteinNM_074387.3
TrEMBLUniProtAccO62377
UniProt_GCRPUniProtAccO62377
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
221 Sep 2004 09:38:16WBPerson1971Name_changeCGC_namecyp-34A2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyp
Allele (146)
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (154)
Paralog (44)
Structured_descriptionAutomated_descriptionPredicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); hematologic cancer (multiple); and renal fibrosis. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2J2 (cytochrome P450 family 2 subfamily J member 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDST10H4.11
Corresponding_transcriptT10H4.11.1
Other_sequenceCSC01939_1
FC555297.1
EY471056.1
CJC00815_1
FD515051.1
Acan_isotig21475
ACC21350_1
Associated_featureWBsf235045
WBsf235046
Experimental_infoRNAi_resultWBRNAi00035454Inferred_automaticallyRNAi_primary
WBRNAi00092672Inferred_automaticallyRNAi_primary
WBRNAi00053074Inferred_automaticallyRNAi_primary
WBRNAi00018564Inferred_automaticallyRNAi_primary
Expr_patternExpr1028643
Expr1156683
Expr2010727
Expr2028965
Drives_constructWBCnstr00030459
Construct_productWBCnstr00030459
Microarray_results (19)
Expression_cluster (247)
Interaction (101)
Map_infoMapVPosition7.66055Error0.000928
PositivePositive_cloneT10H4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene