WormBase Tree Display for Gene: WBGene00010988
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| WBGene00010988 | SMap | S_parent | Sequence | R03D7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | metr-1 | Person_evidence | WBPerson1711 | |||||
| Sequence_name | R03D7.1 | ||||||||
| Molecular_name | R03D7.1 | ||||||||
| R03D7.1.1 | |||||||||
| CE01609 | |||||||||
| Other_name | CELE_R03D7.1 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | metr-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 20 Apr 2011 10:05:24 | WBPerson2970 | Name_change | CGC_name | metr-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | metr | ||||||||
| Allele (55) | |||||||||
| Strain | WBStrain00001842 | ||||||||
| WBStrain00002165 | |||||||||
| WBStrain00031469 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00015512 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00020491 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | metr-1 encodes a protein orthologous to the human gene Methionine synthase (MTR), which is involved in the conversion of homocysteine to form methionine. | Paper_evidence | WBPaper00042203 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 07 May 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable methionine synthase activity. Predicted to be involved in homocysteine metabolic process; methionine biosynthetic process; and tetrahydrofolate metabolic process. Predicted to be located in cytosol. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; and hematologic cancer (multiple). Is an ortholog of human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:9352 | Homo sapiens | Paper_evidence | WBPaper00042203 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 13 Mar 2023 00:00:00 | ||||||||
| Potential_model (14) | |||||||||
| Models_disease_asserted | WBDOannot00000175 | ||||||||
| Molecular_info | Corresponding_CDS | R03D7.1 | |||||||
| Corresponding_transcript | R03D7.1.1 | ||||||||
| Other_sequence (51) | |||||||||
| Associated_feature | WBsf222084 | ||||||||
| WBsf222085 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00071221 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00034551 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090587 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051170 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00106971 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017346 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram417 | ||||||||
| Chronogram1093 | |||||||||
| Expr6447 | |||||||||
| Expr6448 | |||||||||
| Expr1028258 | |||||||||
| Expr1034818 | |||||||||
| Expr1154877 | |||||||||
| Expr2013538 | |||||||||
| Expr2031772 | |||||||||
| Drives_construct | WBCnstr00002636 | ||||||||
| WBCnstr00004383 | |||||||||
| Regulate_expr_cluster | WBPaper00060951:metr-1(os521)_downregulated | ||||||||
| WBPaper00060951:metr-1(os521)_upregulated | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (213) | |||||||||
| Interaction (110) | |||||||||
| Map_info | Map | II | Position | 3.13342 | Error | 0.000132 | |||
| Positive | Positive_clone | R03D7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (25) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
