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WormBase Tree Display for Gene: WBGene00010700

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Name Class

WBGene00010700SMapS_parentSequenceK09A9
IdentityVersion2
NameCGC_namenipi-3Person_evidenceWBPerson168
Sequence_nameK09A9.1
Molecular_nameK09A9.1
K09A9.1.1
CE42581
Other_nameCELE_K09A9.1Accession_evidenceNDBBX284606
Public_namenipi-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
217 Apr 2008 15:10:27WBPerson2970Name_changeCGC_namenipi-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnipi
Allele (47)
StrainWBStrain00003315
WBStrain00021982
WBStrain00021978
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (28)
ParalogWBGene00007007Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00010681Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00011304Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionnipi-3 encodes a kinase similar to the human kinase Tribbles homolog 1; nipi-3 functions in the innate immune response, likely upstream of the SEK-1 MAPKK, to upregulate expression of NLP-29, an antimicrobial peptide, in response to fungal infection.Paper_evidenceWBPaper00031666
Curator_confirmedWBPerson1843
Date_last_updated04 Feb 2011 00:00:00
Automated_descriptionEnables DNA-binding transcription factor binding activity. Involved in defense response to other organism and regulation of gene expression. Predicted to be located in nucleus. Expressed in CAN; hypodermis; motor neurons; pharynx; and touch receptor neurons. Is an ortholog of human TRIB1 (tribbles pseudokinase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSK09A9.1
Corresponding_CDS_historyK09A9.1:wp98
K09A9.1:wp190
Corresponding_transcriptK09A9.1.1
Other_sequenceCR04824
CRC00651_1
CBC12317_1
CJC06811_1
CR06179
Associated_featureWBsf648817
WBsf648818
WBsf655238
WBsf655239
WBsf663659
WBsf663660
WBsf982306
WBsf1008281
Experimental_infoRNAi_result (27)
Expr_patternChronogram892
Expr6374
Expr8070
Expr12563
Expr13665
Expr1027431
Expr1034682
Expr1154069
Expr2014263
Expr2032503
Drives_constructWBCnstr00000508
WBCnstr00003786
WBCnstr00006335
WBCnstr00007217
WBCnstr00013088
WBCnstr00031209
Construct_productWBCnstr00000508
WBCnstr00006335
WBCnstr00007219
WBCnstr00007220
WBCnstr00007221
WBCnstr00007222
WBCnstr00031209
Regulate_expr_clusterWBPaper00050515:nipi-3(fr4)_downregulated
WBPaper00050515:nipi-3(fr4)_upregulated
Microarray_results (24)
Expression_cluster (205)
Interaction (13)
WBProcessWBbiopr:00000001
WBbiopr:00000039
Map_infoMapXPosition22.9309Error0.001583
PositivePositive_cloneK09A9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (18)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene