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WormBase Tree Display for Gene: WBGene00010484

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Name Class

WBGene00010484SMapS_parentSequenceK01H12
IdentityVersion2
NameCGC_namedph-3Person_evidenceWBPerson237
Sequence_nameK01H12.1
Molecular_nameK01H12.1a
K01H12.1a.1
CE03453
K01H12.1b
CE44584
K01H12.1b.1
Other_nameCELE_K01H12.1Accession_evidenceNDBBX284604
Public_namedph-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
218 Aug 2009 11:24:59WBPerson9133Name_changeCGC_namedph-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdph
Allele (12)
StrainWBStrain00026526
RNASeq_FPKM (74)
GO_annotation00007349
00069953
00069954
00069955
00069956
00069957
00069958
00069959
00117642
00117643
Ortholog (33)
Structured_descriptionConcise_descriptiondph-3 encodes a small protein conserved in diverse eukaryotes, with a CSL motif (a probable zinc finger, sometimes found associated with the N-terminal domain of DnaJ protein); DPH-3 is probably a small subunit or ancillary protein of RNA polymerase II Elongator or of a hypothetical diphthamide synthase complex; DPH-3 is orthologous to mammalian DESR1 (diphtheria toxin and Pseudomonas exotoxin A sensitivity required gene 1) and S. cerevisiae KTI11; DESR1, and probably KTI11, enables the first step in posttranslational modification of histidine to dipthamide.Paper_evidenceWBPaper00005654
WBPaper00013055
WBPaper00013218
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated18 Aug 2009 00:00:00
Automated_descriptionPredicted to enable ferrous iron binding activity and iron chaperone activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Located in nucleus. Is an ortholog of human DPH3 (diphthamide biosynthesis 3) and DPH3P1 (diphthamide biosynthesis 3 pseudogene 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS290 version of WormBase
Date_last_updated11 Sep 2023 00:00:00
Molecular_infoCorresponding_CDSK01H12.1a
K01H12.1b
Corresponding_transcriptK01H12.1a.1
K01H12.1b.1
Other_sequence (56)
Associated_featureWBsf646248
WBsf228860
Transcription_factorWBTranscriptionFactor000379
Experimental_infoRNAi_resultWBRNAi00025838Inferred_automaticallyRNAi_primary
WBRNAi00027396Inferred_automaticallyRNAi_primary
WBRNAi00016414Inferred_automaticallyRNAi_primary
WBRNAi00025839Inferred_automaticallyRNAi_primary
WBRNAi00092977Inferred_automaticallyRNAi_primary
WBRNAi00115818Inferred_automaticallyRNAi_primary
WBRNAi00049641Inferred_automaticallyRNAi_primary
WBRNAi00033835Inferred_automaticallyRNAi_primary
Expr_patternExpr9502
Expr1019874
Expr1034578
Expr1153368
Expr2011049
Expr2029286
Drives_constructWBCnstr00031386
Construct_productWBCnstr00014067
WBCnstr00031386
Microarray_results (21)
Expression_cluster (117)
Interaction (49)
Map_infoMapIVPosition4.37903Error0.001128
PositivePositive_cloneK01H12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027309
WBPaper00036232
WBPaper00038444
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene