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WormBase Tree Display for Gene: WBGene00009977

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Name Class

WBGene00009977SMapS_parentSequenceF53C11
IdentityVersion2
NameCGC_nameswan-1Person_evidenceWBPerson389
Sequence_nameF53C11.8
Molecular_nameF53C11.8
F53C11.8.1
CE10918
Other_nameCELE_F53C11.8Accession_evidenceNDBBX284605
Public_nameswan-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:50WBPerson1971EventImportedInitial conversion from CDS class of WS125
228 Jul 2005 14:04:14WBPerson2970Name_changeCGC_nameswan-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classswan
Allele (61)
StrainWBStrain00024136
WBStrain00022427
WBStrain00022428
WBStrain00022436
WBStrain00022437
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP5400
Ortholog (33)
ParalogWBGene00009976Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionswan-1 encodes a protein that belongs to the family of AN11 WD repeat proteins; WD repeats are considered to form a scaffold for protein-protein interactions; SWAN-1 was initially identified as a protein that interacts with UNC-115 and the RAC proteins-CED-10, MIG-2 and RAC-2; genetic interaction studies with the Rac genes indicate that swan-1 is a negative regulator of Rac GTPase function during morphogenesis and phagocytosis of apoptotic cells; swan-1 is expressed in most cells throughout development and is predominant in the cytoplasm.Paper_evidenceWBPaper00028497
Curator_confirmedWBPerson324
Date_last_updated01 Oct 2008 00:00:00
Automated_descriptionEnables LIM domain binding activity and small GTPase binding activity. Involved in several processes, including regulation of cellular component organization; response to heat; and response to osmotic stress. Located in cytoplasm. Expressed in several structures, including neuroblasts and neurons. Is an ortholog of human DCAF7 (DDB1 and CUL4 associated factor 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF53C11.8
Corresponding_transcriptF53C11.8.1
Other_sequence (34)
Associated_featureWBsf655606
WBsf982032
WBsf1001891
WBsf1020763
WBsf234872
WBsf234873
Experimental_infoRNAi_resultWBRNAi00048106Inferred_automaticallyRNAi_primary
WBRNAi00015493Inferred_automaticallyRNAi_primary
WBRNAi00103046Inferred_automaticallyRNAi_primary
WBRNAi00032685Inferred_automaticallyRNAi_primary
WBRNAi00084262Inferred_automaticallyRNAi_primary
Expr_patternExpr8273
Expr1013192
Expr1034348
Expr1151916
Expr2017148
Expr2035284
Drives_constructWBCnstr00013229
WBCnstr00019891
WBCnstr00031770
Construct_productWBCnstr00019891
WBCnstr00031770
Microarray_results (21)
Expression_cluster (128)
Interaction (31)
Map_infoMapVPosition5.5935Error0.002407
PositivePositive_cloneF53C11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5333
4207
4873
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene