WormBase Tree Display for Gene: WBGene00006971
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| WBGene00006971 | SMap | S_parent | Sequence | R13F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | zak-1 | Person_evidence | WBPerson1315 | |||||
| Sequence_name | R13F6.6 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | CELE_R13F6.6 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | zak-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:44 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | zak | ||||||||
| Allele (57) | |||||||||
| Strain | WBStrain00051212 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (29) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Concise_description | zak-1 encodes a mitogen-activated protein kinase kinase kinase (MAPKKK) that is orthologous to mammalian zipper sterile-motif kinases (ZAKs); ZAK-1 is predicted to play a role in regulation of MAPK signaling cascades and large-scale RNAi experiments indicate that its activity is required for proper embryonic and larval development. | Paper_evidence | WBPaper00004403 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00013126 | |||||||||
| WBPaper00024295 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 14 Aug 2006 00:00:00 | ||||||||
| Automated_description | Enables MAP kinase kinase kinase activity. Involved in stress-activated MAPK cascade. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in centronuclear myopathy 6 with fiber-type disproportion. Is an ortholog of human MAP3K20 (mitogen-activated protein kinase kinase kinase 20). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111221 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17797) | ||||
| Molecular_info | Corresponding_CDS | R13F6.6a | |||||||
| R13F6.6b | |||||||||
| R13F6.6c | |||||||||
| Corresponding_CDS_history | R13F6.6:wp82 | ||||||||
| R13F6.6a:wp147 | |||||||||
| R13F6.6a:wp225 | |||||||||
| Corresponding_transcript | R13F6.6a.1 | ||||||||
| R13F6.6a.2 | |||||||||
| R13F6.6b.1 | |||||||||
| R13F6.6b.2 | |||||||||
| R13F6.6c.1 | |||||||||
| Other_sequence | AS11924 | ||||||||
| JI165508.1 | |||||||||
| CJC06263_1 | |||||||||
| MC05171 | |||||||||
| CR05032 | |||||||||
| HGC05974 | |||||||||
| HG09306 | |||||||||
| ASC04037_1 | |||||||||
| CRC02818_1 | |||||||||
| MCC05841_1 | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr1010577 | ||||||||
| Expr1032978 | |||||||||
| Expr1155575 | |||||||||
| Expr2018122 | |||||||||
| Expr2036259 | |||||||||
| Drives_construct | WBCnstr00034062 | ||||||||
| Construct_product | WBCnstr00034062 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (123) | |||||||||
| Map_info | Map | III | Position | -0.926358 | Error | 0.00147 | |||
| Positive | Positive_clone | R13F6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4762 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00018823 | ||||||||
| WBPaper00019662 | |||||||||
| WBPaper00024295 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059543 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
