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WormBase Tree Display for Gene: WBGene00006667

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Name Class

WBGene00006667EvidencePerson_evidenceWBPerson655
SMapS_parentSequenceF29F11
IdentityVersion1
NameCGC_nametwk-12Person_evidenceWBPerson655
Sequence_nameF29F11.4
Molecular_nameF29F11.4
F29F11.4.1
CE48353
Other_nametwk-9Person_evidenceWBPerson655
CELE_F29F11.4Accession_evidenceNDBBX284605
Public_nametwk-12
DB_infoDatabaseAceViewgene5L149
WormQTLgeneWBGene00006667
WormFluxgeneWBGene00006667
NDBlocus_tagCELE_F29F11.4
PanthergeneCAEEL|WormBase=WBGene00006667|UniProtKB=Q19907
familyPTHR11003
NCBIgene192074
RefSeqproteinNM_073330.5
SwissProtUniProtAccQ19907
UniProt_GCRPUniProtAccQ19907
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtwk
Allele (43)
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (32)
Paralog (47)
Structured_descriptionConcise_descriptiontwk-12 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; as loss of TWK-12 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of TWK-12 in C. elegans development and/or behavior is not yet known; TWK-12 may, however, function redundantly with other TWK channels; the TWK-12 expression pattern has not been determined.Paper_evidenceWBPaper00004644
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF29F11.4
Corresponding_CDS_historyF29F11.4:wp131
F29F11.4:wp237
Corresponding_transcriptF29F11.4.1
Associated_featureWBsf1001160
WBsf1001161
WBsf1020331
WBsf232408
Experimental_infoRNAi_resultWBRNAi00045933Inferred_automaticallyRNAi_primary
WBRNAi00014110Inferred_automaticallyRNAi_primary
Expr_patternExpr1019450
Expr1149833
Expr2017640
Expr2035780
Microarray_results (17)
Expression_cluster (112)
InteractionWBInteraction000121778
WBInteraction000133844
WBInteraction000138601
WBInteraction000566457
WBInteraction000566736
WBInteraction000580459
Map_infoMapVPosition2.70767Error0.000525
PositivePositive_cloneF29F11Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00006402
WBPaper00013489
WBPaper00026748
WBPaper00038491
WBPaper00055090
Remarktwk-12 was connected to K01D12.4CGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene