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WormBase Tree Display for Gene: WBGene00006467

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Name Class

WBGene00006467SMapS_parentSequenceC01B7
IdentityVersion4
NameCGC_namemagu-2Person_evidenceWBPerson260
Sequence_nameC01B7.4
Molecular_nameC01B7.4a
C01B7.4a.1
CE52786
C01B7.4b
CE06728
C01B7.4b.1
Other_nametag-117Person_evidenceWBPerson51134
WBPerson21950
CELE_C01B7.4Accession_evidenceNDBBX284605
Public_namemagu-2
DB_infoDatabaseAceViewgene5J272
WormQTLgeneWBGene00006467
WormFluxgeneWBGene00006467
NDBlocus_tagCELE_C01B7.4
PanthergeneCAEEL|WormBase=WBGene00006467|UniProtKB=A0A3B1DQX2
familyPTHR23122
NCBIgene3565703
RefSeqproteinNM_001368460.3
NM_001392569.1
TrEMBLUniProtAccA0A3B1DQX2
Q17549
UniProt_GCRPUniProtAccA0A3B1DQX2
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
207 Feb 2012 16:30:56WBPerson2970Name_changeCGC_namemagu-2
317 Sep 2018 14:44:56WBPerson4025EventAcquires_mergeWBGene00015276
406 Sep 2021 12:29:06WBPerson1983Name_changeOther_nametag-117
Acquires_mergeWBGene00015276
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmagu
Allele (111)
StrainWBStrain00001351
WBStrain00031792
WBStrain00035753
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (38)
ParalogWBGene00002991Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00016841Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00021914Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionmagu-2 encodes a protein with similarity to the MAGUK (membrane-associated guanylate kinase) family of proteins; loss of magu-2 activity in large-scale RNAi screens can result in embryonic lethality with low, reproducible chromosome segregation defects; magu-2 exhibits genetic interactions with sem-5 and glp-1.Paper_evidenceWBPaper00025054
WBPaper00031036
Curator_confirmedWBPerson1843
Date_last_updated06 Jan 2011 00:00:00
Automated_descriptionPredicted to be involved in several processes, including establishment or maintenance of cell polarity; morphogenesis of an epithelial sheet; and protein localization to plasma membrane. Predicted to be located in adherens junction and plasma membrane. Expressed in head; hypodermis; and pharyngeal muscle cell. Is an ortholog of human PALS1 (protein associated with LIN7 1, MAGUK p55 family member).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC01B7.4a
C01B7.4b
Corresponding_CDS_historyC01B7.4:wp267
Corresponding_transcriptC01B7.4a.1
C01B7.4b.1
Other_sequence (25)
Associated_featureWBsf652873
WBsf717246
WBsf718362
WBsf718363
WBsf1000758
WBsf1000759
WBsf1000760
WBsf1000761
WBsf1020096
WBsf1020097
Experimental_infoRNAi_resultWBRNAi00028272Inferred_automaticallyRNAi_primary
WBRNAi00067794Inferred_automaticallyRNAi_primary
WBRNAi00077325Inferred_automaticallyRNAi_primary
WBRNAi00039280Inferred_automaticallyRNAi_primary
WBRNAi00009904Inferred_automaticallyRNAi_primary
WBRNAi00067982Inferred_automaticallyRNAi_primary
WBRNAi00009903Inferred_automaticallyRNAi_primary
WBRNAi00103157Inferred_automaticallyRNAi_primary
WBRNAi00028271Inferred_automaticallyRNAi_primary
WBRNAi00039281Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00002244
WBCnstr00028966
WBCnstr00041995
Construct_productWBCnstr00028966
WBCnstr00041995
Regulate_expr_clusterWBPaper00062554:MAGU-2_interacting
Microarray_results (36)
Expression_cluster (237)
Interaction (65)
Map_infoMapVPosition1.61461Error0.004441
PositivePositive_cloneC01B7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4356
Pseudo_map_position
ReferenceWBPaper00031333
WBPaper00035956
WBPaper00038491
WBPaper00051918
WBPaper00055090
WBPaper00058545
WBPaper00059621
WBPaper00062554
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
Moved tag-117 from magu-1 to magu-2 where it belongs, seems like a very old (2013) misassignment.
MethodGene