WormBase Tree Display for Gene: WBGene00004773
expand all nodes | collapse all nodes | view schema
| WBGene00004773 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | sem-4 | Person_evidence | WBPerson268 | |||||
| Sequence_name | F15C11.1 | ||||||||
| Molecular_name | F15C11.1 | ||||||||
| F15C11.1.1 | |||||||||
| CE17673 | |||||||||
| Other_name | CELE_F15C11.1 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | sem-4 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sem | ||||||||
| Allele (118) | |||||||||
| Legacy_information | [C.elegansII] n1378 : Egl, hermaphrodite sex muscles fail to differentiate; additional axon and lineage defects. ME0 (severe Mab), HME3. OA3: h769, n2087, n1971 (stronger allele, two mesodermal and six neuronal cell types pleiotropically affected; 2 additional touch cells formed in tail), etc. Cloned: encodes predicted protein with 6 C2H2 zincfinger motifs. [Desai et al. 1988; Mitani et al. 1993; MT; NH; TU] | ||||||||
| Strain (13) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (25) | |||||||||
| Ortholog (50) | |||||||||
| Paralog | WBGene00017430 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | sem-4 encodes a zinc-finger protein; sem-4 activity is required for proper development of cells in neuronal, mesodermal, and vulval cell lineages; sem-4 activity is also required for transdifferentiation of the Y rectal cell to the PDA neuron during larval development; a SEM-4::GFP reporter fusions are widely expressed with fluorescence seen in a number of different cell types including neurons, hypodermis, vulval precursor cells, and tail blast cells such as B and F. | Paper_evidence | WBPaper00002518 | |||||
| WBPaper00004300 | |||||||||
| WBPaper00040964 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 04 Dec 2012 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell differentiation; regulation of transcription by RNA polymerase II; and response to oxidative stress. Located in nucleus. Expressed in several structures, including HSN; M lineage cell; rectal epithelial cell; rectum; and tail hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Duane retraction syndrome; Duane-radial ray syndrome; and Holt-Oram syndrome. Is an ortholog of human SALL1 (spalt like transcription factor 1) and SALL3 (spalt like transcription factor 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (13) | ||||||||
| Molecular_info | Corresponding_CDS | F15C11.1 | |||||||
| Corresponding_transcript | F15C11.1.1 | ||||||||
| Other_sequence (20) | |||||||||
| Associated_feature (28) | |||||||||
| Gene_product_binds (380) | |||||||||
| Transcription_factor | WBTranscriptionFactor000098 | ||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00000795 | ||||||||
| WBCnstr00000796 | |||||||||
| WBCnstr00035398 | |||||||||
| Construct_product | WBCnstr00000795 | ||||||||
| WBCnstr00000796 | |||||||||
| WBCnstr00015364 | |||||||||
| WBCnstr00016866 | |||||||||
| WBCnstr00035398 | |||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (199) | |||||||||
| Interaction (185) | |||||||||
| WBProcess | WBbiopr:00000020 | ||||||||
| WBbiopr:00000023 | |||||||||
| WBbiopr:00000115 | |||||||||
| Map_info | Map | I | Position | 1.65489 | Error | 0.003417 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | E02H2 | |||||||
| F15C11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | Multi_point | 1446 | |||||||
| 1447 | |||||||||
| 2089 | |||||||||
| 4030 | |||||||||
| 5026 | |||||||||
| 5509 | |||||||||
| Pos_neg_data | 5332 | ||||||||
| 5341 | |||||||||
| 5349 | |||||||||
| 5365 | |||||||||
| 5680 | |||||||||
| Reference (87) | |||||||||
| Method | Gene |
