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WormBase Tree Display for Gene: WBGene00004350

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Name Class

WBGene00004350SMapS_parentSequenceF56B6
IdentityVersion2
NameCGC_namergs-7Person_evidenceWBPerson330
Sequence_nameF56B6.2
Molecular_name (27)
Other_nameCELE_F56B6.2Accession_evidenceNDBBX284606
Public_namergs-7
DB_infoDatabaseAceViewgeneXE175
WormQTLgeneWBGene00004350
WormFluxgeneWBGene00004350
NDBlocus_tagCELE_F56B6.2
PanthergeneCAEEL|WormBase=WBGene00004350|UniProtKB=Q8WQC0
familyPTHR10845
NCBIgene180645
RefSeqproteinNM_001129682.5
NM_001373262.3
NM_001373261.4
NM_001374994.1
NM_001029543.5
NM_001129681.4
NM_001373260.4
NM_001029544.6
NM_076209.7
SwissProtUniProtAccQ8WQC0
TrEMBLUniProtAccA0A4V0IJG9
Q1W0R0
H2KYQ7
A0A4V0IKM4
A0A4V0ILX5
H2KYQ8
UniProt_GCRPUniProtAccQ8WQC0
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
203 Dec 2004 16:13:27WBPerson2970EventAcquires_mergeWBGene00018936
Acquires_mergeWBGene00018936
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrgs
AlleleWBVar00275085Inferred_automaticallyFrom strain object: LX658
WBVar00275090Inferred_automaticallyFrom strain object: LX677
WBVar01134624
WBVar01134625
WBVar01134626
WBVar01134627
WBVar01134628
WBVar01134629
WBVar01134630
WBVar00499323
WBVar01134631
WBVar00499324
WBVar01134632
WBVar01134633
WBVar00499325
WBVar01134634
WBVar00499326
WBVar01134635
WBVar00499327
WBVar01914193
WBVar00499328
WBVar01134636
WBVar02121347
WBVar00499329
WBVar01134637
WBVar01498609
WBVar00499330
WBVar01134638
WBVar00499331
WBVar01134639
WBVar01134640
WBVar00499332
WBVar00499333
WBVar01825060
WBVar01134641
WBVar00499334
WBVar01134642
WBVar01825061
WBVar00499335
WBVar01134643
WBVar01134644
WBVar00499336
WBVar01134645
WBVar00499337
WBVar01134646
WBVar00499338
WBVar00499339
WBVar01830094
WBVar01134647
WBVar00499340
WBVar01134648
WBVar00499341
WBVar01544459
WBVar01134649
WBVar00499342
WBVar01134650
WBVar00499343
WBVar00499344
WBVar00499345
WBVar00499346
WBVar00499347
WBVar00499348
WBVar00077144
WBVar00499349
WBVar00499350
WBVar00499351
WBVar00093672
WBVar00069879
WBVar02026935
WBVar01486700
WBVar01498854
WBVar01814062
WBVar01814063
WBVar01814064
WBVar01980165
WBVar01980166
WBVar01134523
WBVar01980167
WBVar01134524
WBVar01134525
WBVar01134526
WBVar01134527
WBVar01134528
WBVar01134529
WBVar01134530
WBVar01134531
WBVar01134532
WBVar01134533
WBVar01134534
WBVar01134535
WBVar01134536
WBVar01134537
WBVar01134538
WBVar02151154
WBVar01134539
WBVar01134540
WBVar01134541
WBVar01134542
WBVar01134543
WBVar01134544
WBVar01134545
WBVar01134546
WBVar01134547
WBVar01134548
WBVar01134549
WBVar01134550
WBVar02001140
WBVar01134551
WBVar01134552
WBVar01134553
WBVar01134554
WBVar01134555
WBVar01134556
WBVar01134557
WBVar01134558
WBVar01134559
WBVar01499636
WBVar01134560
WBVar01134561
WBVar01134562
WBVar01134563
WBVar01134564
WBVar01134565
WBVar01134566
WBVar01134567
WBVar01134568
WBVar01134569
WBVar01134570
WBVar01786826
WBVar01134571
WBVar01134572
WBVar01134573
WBVar01134574
WBVar02055369
WBVar01134575
WBVar01134576
WBVar01134577
WBVar01134578
WBVar01134579
WBVar01134580
WBVar01134581
WBVar01134582
WBVar01134583
WBVar00266417
WBVar01134584
WBVar01134585
WBVar01134586
WBVar01134587
WBVar01134588
WBVar01134589
WBVar01134590
WBVar01134591
WBVar01134592
WBVar01134593
WBVar01134594
WBVar01134595
WBVar01134596
WBVar01134597
WBVar01619525
WBVar01134598
WBVar01134599
WBVar01134600
WBVar01134601
WBVar01468311
WBVar01134602
WBVar01468312
WBVar01134603
WBVar01468313
WBVar01134604
WBVar02122052
WBVar01468314
WBVar01134605
WBVar01468315
WBVar01134606
WBVar01134607
WBVar01134608
WBVar01134609
WBVar01134610
WBVar01134611
WBVar01134612
WBVar02139035
WBVar01134613
WBVar01134614
WBVar02139036
WBVar01134615
WBVar01134616
WBVar01134617
WBVar01134618
WBVar01134619
WBVar01134620
WBVar01134621
WBVar01134622
WBVar01134623
WBVar01500067
StrainWBStrain00026370
WBStrain00026372
WBStrain00032622
WBStrain00034758
RNASeq_FPKM (74)
GO_annotation00021823
00021824
00021825
00085200
00085201
Ortholog (38)
Paralog (12)
Structured_descriptionConcise_descriptionrgs-7 encodes three isoforms of an atypical regulator of G protein signaling (RGS) protein that contains both a C2 and an RGS domain, and that binds EGL-30 via both domains, similar in organization to mammalian PDZ-RGS3; the RGS domain has GTPase activator protein (GAP) activity in vitro on mammalian G[alphai]3; RGS-7 thus may stably bind EGL-30 at all stages of EGL-30's GTPase cycle, might organize EGL-30 into a stable multiprotein signalling complex (with GTP[gamma]S), and might persistently inhibit EGL-30 when triggered by calcium or phospholipids; rgs-7 has no obvious function in mass RNAi assaysPaper_evidenceWBPaper00005654
WBPaper00005958
WBPaper00013066
Curator_confirmedWBPerson567
Date_last_updated18 Jun 2007 00:00:00
Automated_descriptionEnables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Located in cell cortex. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS4 (regulator of G protein signaling 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF56B6.2a
F56B6.2b
F56B6.2c
F56B6.2e
F56B6.2f
F56B6.2g
F56B6.2h
F56B6.2i
F56B6.2j
Corresponding_CDS_historyF56B6.2d:wp271
Corresponding_transcriptF56B6.2a.1
F56B6.2b.1
F56B6.2c.1
F56B6.2e.1
F56B6.2f.1
F56B6.2g.1
F56B6.2h.1
F56B6.2i.1
F56B6.2j.1
Other_sequence (21)
Associated_feature (27)
Experimental_infoRNAi_resultWBRNAi00048645Inferred_automaticallyRNAi_primary
WBRNAi00048644Inferred_automaticallyRNAi_primary
WBRNAi00032932Inferred_automaticallyRNAi_primary
WBRNAi00015785Inferred_automaticallyRNAi_primary
Expr_patternExpr3108
Expr1025711
Expr1032168
Expr1152407
Expr1200208
Expr2015330
Expr2033564
Drives_constructWBCnstr00011142
WBCnstr00035547
Construct_productWBCnstr00011142
WBCnstr00035547
Microarray_results (53)
Expression_cluster (147)
Interaction (11)
WBProcessWBbiopr:00000017
Map_infoMapXPosition-10.1117Error0.033929
PositivePositive_cloneF56B6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5042
Pseudo_map_position
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene