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WormBase Tree Display for Gene: WBGene00004244

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Name Class

WBGene00004244SMapS_parentSequenceC30G12
IdentityVersion2
NameCGC_namepuf-8Person_evidenceWBPerson320
Sequence_nameC30G12.7
Molecular_nameC30G12.7
C30G12.7.1
CE37486
Other_nameteg-2Person_evidenceWBPerson555
CELE_C30G12.7Accession_evidenceNDBBX284602
Public_namepuf-8
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
214 Aug 2012 14:38:21WBPerson2970EventAcquires_mergeWBGene00006564
Name_changeOther_nameteg-2
Acquires_mergeWBGene00006564
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpuf
Allele (42)
StrainWBStrain00022254
WBStrain00022619
WBStrain00022166
WBStrain00022639
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP2292
Ortholog (33)
ParalogWBGene00001401Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001402Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004239Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004241Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004242Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004243Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004245Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00022257Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionpuf-8 encodes a member of the PUF family of RNA binding proteins.Paper_evidenceWBPaper00042132
Curator_confirmedWBPerson1843
Date_last_updated01 Apr 2014 00:00:00
Automated_descriptionEnables mRNA 3'-UTR binding activity. Involved in male meiotic nuclear division; negative regulation of MAPK cascade; and spermatogenesis. Located in P granule and nuclear periphery. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; germ line; sperm; and vulva. Used to study obesity. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Is an ortholog of human PUM1 (pumilio RNA binding family member 1) and PUM2 (pumilio RNA binding family member 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00061889
Curator_confirmedWBPerson324
Date_last_updated28 Jun 2022 00:00:00
Potential_modelDOID:0111743Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:14957)
Models_disease_in_annotationWBDOannot00001263
Molecular_infoCorresponding_CDSC30G12.7
Corresponding_CDS_historyC30G12.7:wp130
Corresponding_transcriptC30G12.7.1
Other_sequenceCR01371
CRC02691_1
CJC01330_1
Associated_featureWBsf019217
WBsf019218
WBsf223321
Gene_product_bindsWBsf899537
WBsf899538
WBsf899539
WBsf899540
Experimental_infoRNAi_result (24)
Expr_pattern (11)
Drives_construct (12)
Construct_productWBCnstr00005726
WBCnstr00005727
WBCnstr00017042
WBCnstr00017521
WBCnstr00017549
WBCnstr00017550
WBCnstr00017551
WBCnstr00017552
WBCnstr00035610
Regulate_expr_clusterWBPaper00045618:puf-8_downregulated
WBPaper00045618:puf-8_upregulated
Microarray_results (19)
Expression_cluster (127)
Interaction (43)
WBProcessWBbiopr:00000069
Map_infoMapIIPosition0.500136Error0.000128
PositivePositive_cloneC30G12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4171
4615
5564
3796
3826
Pseudo_map_position
Reference (78)
Remarksequence connection from [Bernstein M, Wickens MP]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene