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WormBase Tree Display for Gene: WBGene00004076

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Name Class

WBGene00004076SMapS_parentSequenceW09B6
IdentityVersion2
NameCGC_namepod-2Person_evidenceWBPerson26
Sequence_nameW09B6.1
Molecular_name (12)
Other_namephi-47Person_evidenceWBPerson2582
CELE_W09B6.1Accession_evidenceNDBBX284602
Public_namepod-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
219 Aug 2005 11:54:06WBPerson2970EventAcquires_mergeWBGene00021102
Acquires_mergeWBGene00021102
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpod
Allele (335)
Possibly_affected_byWBVar02153249
StrainWBStrain00008572
WBStrain00049317
WBStrain00054654
WBStrain00054709
RNASeq_FPKM (74)
GO_annotation (25)
Ortholog (46)
ParalogWBGene00012131Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004258Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00009319Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00017864Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionpod-2 encodes an acetyl-CoA carboxylase; by sequence similarity, POD-2 is predicted to catalyze the first step in de novo fatty acid biosynthesis; pod-2 is required for proper embryonic polarity and for osmotic protection of the eggshell; pod-2 activity is also required for molting.Paper_evidenceWBPaper00004706
WBPaper00005095
WBPaper00024324
WBPaper00026763
Curator_confirmedWBPerson1843
Date_last_updated14 Oct 2008 00:00:00
Automated_descriptionPredicted to enable acetyl-CoA carboxylase activity. Involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; nematode larval development; and polarity specification of anterior/posterior axis. Predicted to be located in endoplasmic reticulum membrane and mitochondrion. Expressed in CANL; CANR; and excretory duct. Used to study muscular disease. Is an ortholog of human ACACA (acetyl-CoA carboxylase alpha).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:0080000Homo sapiensPaper_evidenceWBPaper00061805
Curator_confirmedWBPerson324
Date_last_updated25 Apr 2022 00:00:00
Models_disease_in_annotationWBDOannot00001162
Molecular_infoCorresponding_CDSW09B6.1a
W09B6.1b
W09B6.1c
Corresponding_transcriptW09B6.1a.1
W09B6.1a.2
W09B6.1a.3
W09B6.1a.4
W09B6.1b.1
W09B6.1c.1
Other_sequence (71)
Associated_feature (18)
Experimental_infoRNAi_result (24)
Expr_patternChronogram1203
Expr6859
Expr9289
Expr12921
Expr15196
Expr1021344
Expr1031965
Expr1158544
Expr2014988
Expr2033223
Drives_constructWBCnstr00003313
WBCnstr00013878
WBCnstr00023095
Regulate_expr_clusterWBPaper00038215:pod-2(RNAi)_regulated
Microarray_results (29)
Expression_cluster (167)
Interaction (107)
Map_infoMapIIPosition-15.5649
PositivePositive_cloneW09B6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5516
4672
Pseudo_map_position
Reference (45)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene