WormBase Tree Display for Gene: WBGene00003607
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| WBGene00003607 | Evidence | Paper_evidence | WBPaper00003416 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| WBPaper00004181 | |||||||||
| SMap | S_parent | Sequence | F33D4 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | nhr-8 | Person_evidence | WBPerson600 | |||||
| Sequence_name | F33D4.1 | ||||||||
| Molecular_name | F33D4.1a | ||||||||
| F33D4.1a.1 | |||||||||
| CE33927 | |||||||||
| F33D4.1b | |||||||||
| CE33928 | |||||||||
| F33D4.1b.1 | |||||||||
| Other_name | CELE_F33D4.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | nhr-8 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nhr | ||||||||
| Allele (42) | |||||||||
| Legacy_information | NMK. Nuclear hormone receptor superfamily. [AE] | ||||||||
| [C.elegansII] NMK. Nuclear hormone receptor superfamily. YAC Y50A3 etc. [AE] | |||||||||
| Strain | WBStrain00000059 | ||||||||
| WBStrain00051691 | |||||||||
| WBStrain00054632 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (30) | |||||||||
| Paralog (19) | |||||||||
| Structured_description | Concise_description | The nhr-8 gene encodes a nuclear hormone receptor homolog; nhr-8(ok186) mutants have abnormally low resistance to the toxins colchicine and chloroquine. | Paper_evidence | WBPaper00004723 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in cholesterol homeostasis. Located in nucleus. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); autosomal recessive limb-girdle muscular dystrophy type 2B; carcinoma (multiple); and lung disease (multiple). Is an ortholog of human VDR (vitamin D receptor). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (53) | ||||||||
| Molecular_info | Corresponding_CDS | F33D4.1a | |||||||
| F33D4.1b | |||||||||
| Corresponding_CDS_history | F33D4.1a:wp99 | ||||||||
| F33D4.1b:wp99 | |||||||||
| Corresponding_transcript | F33D4.1a.1 | ||||||||
| F33D4.1b.1 | |||||||||
| Other_sequence | Oden_contig20559 | ||||||||
| Oden_isotig10723 | |||||||||
| DN558166.1 | |||||||||
| AYC01323_1 | |||||||||
| HBC03177_1 | |||||||||
| LSC01052_1 | |||||||||
| AE02063 | |||||||||
| ES414143.1 | |||||||||
| Associated_feature | WBsf646108 | ||||||||
| WBsf646109 | |||||||||
| WBsf660331 | |||||||||
| WBsf660332 | |||||||||
| WBsf978331 | |||||||||
| WBsf228565 | |||||||||
| WBsf228566 | |||||||||
| Transcription_factor | WBTranscriptionFactor000264 | ||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern | Expr1351 | ||||||||
| Expr11216 | |||||||||
| Expr1023140 | |||||||||
| Expr1031655 | |||||||||
| Expr1150089 | |||||||||
| Expr2014241 | |||||||||
| Expr2032482 | |||||||||
| Drives_construct | WBCnstr00010232 | ||||||||
| WBCnstr00036006 | |||||||||
| Construct_product | WBCnstr00010232 | ||||||||
| WBCnstr00018225 | |||||||||
| WBCnstr00036006 | |||||||||
| Regulate_expr_cluster | WBPaper00044030:nhr-8(hd117)_downregulated | ||||||||
| WBPaper00044030:nhr-8(hd117)_upregulated | |||||||||
| WBPaper00062446:nhr-8(hd117)_downregulated | |||||||||
| WBPaper00062446:nhr-8(hd117)_upregulated | |||||||||
| WBPaper00062446:nhr-8(ok186)_downregulated | |||||||||
| WBPaper00062446:nhr-8(ok186)_upregulated | |||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (165) | |||||||||
| Interaction (68) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| WBbiopr:00000121 | |||||||||
| Map_info | Map | IV | Position | 3.41773 | Error | 0.007272 | |||
| Positive | Positive_clone | F33D4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Y50A3 | Person_evidence | WBPerson600 | |||||||
| Y53H2 | Person_evidence | WBPerson600 | |||||||
| Y54E12 | Person_evidence | WBPerson600 | |||||||
| Mapping_data | Multi_point | 4520 | |||||||
| Pseudo_map_position | |||||||||
| Reference (53) | |||||||||
| Remark | cm14e12 unnecessary in sequence list. sdm 11/00 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
