WormBase Tree Display for Gene: WBGene00001803
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| WBGene00001803 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C14F11 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | lite-1 | Person_evidence | WBPerson522 | |||||
| WBPerson423 | |||||||||
| Sequence_name | C14F11.3 | ||||||||
| Molecular_name | C14F11.3 | ||||||||
| C14F11.3.1 | |||||||||
| CE29579 | |||||||||
| Other_name | gur-2 | Person_evidence | WBPerson522 | ||||||
| CELE_C14F11.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | lite-1 | ||||||||
| DB_info | Database | AceView | gene | XG846 | |||||
| WormQTL | gene | WBGene00001803 | |||||||
| WormFlux | gene | WBGene00001803 | |||||||
| NDB | locus_tag | CELE_C14F11.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001803|UniProtKB=Q17990 | |||||||
| family | PTHR21143 | ||||||||
| NCBI | gene | 180894 | |||||||
| RefSeq | protein | NM_076642.7 | |||||||
| SwissProt | UniProtAcc | Q17990 | |||||||
| TREEFAM | TREEFAM_ID | TF321557 | |||||||
| UniProt_GCRP | UniProtAcc | Q17990 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 02 Feb 2007 10:20:45 | WBPerson2970 | Name_change | CGC_name | lite-1 | ||||
| Other_name | gur-2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lite | ||||||||
| Allele (104) | |||||||||
| Strain (40) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (28) | |||||||||
| Ortholog (30) | |||||||||
| Paralog | WBGene00001211 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00001804 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| Structured_description | Concise_description | lite-1 encodes a eight-transmembrane protein that is a member of the invertebrate family of Gustatory receptors; LITE-1 functions in neurons as an ultraviolet light receptor required for proper avoidance (photophobic) response to short-wavelength light; ectopic expression of LITE-1 in other tissues, namely body wall and vulval muscles, is sufficient to confer light-responsive muscle contraction; genetic analyses indicate that LITE-1 can stimulate locomotion independent of G protein signaling, as LITE-1 can induce locomotion in near-paralyzed synaptic signaling mutants; further, site of action studies indicate that LITE-1 functions in one or more tail neurons to mediate this light-activated forward locomotion; rescuing LITE-1::GFP fusion proteins reveal expression in the PVT and AVG neurons. | Paper_evidence | WBPaper00032087 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 Aug 2008 00:00:00 | ||||||||
| Automated_description | Enables blue light photoreceptor activity. Involved in locomotory behavior and response to light stimulus. Located in neuron projection; neuronal cell body; and plasma membrane. Expressed in ganglia; hyp3; and pharyngeal neurons. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C14F11.3 | |||||||
| Corresponding_transcript | C14F11.3.1 | ||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00040557 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00028898 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010762 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000949 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr12196 | ||||||||
| Expr12672 | |||||||||
| Expr1025219 | |||||||||
| Expr1144612 | |||||||||
| Expr2013229 | |||||||||
| Expr2031460 | |||||||||
| Drives_construct | WBCnstr00000264 | ||||||||
| WBCnstr00020588 | |||||||||
| WBCnstr00020589 | |||||||||
| WBCnstr00020590 | |||||||||
| WBCnstr00036676 | |||||||||
| Construct_product | WBCnstr00000262 | ||||||||
| WBCnstr00000264 | |||||||||
| WBCnstr00020587 | |||||||||
| WBCnstr00020589 | |||||||||
| WBCnstr00020590 | |||||||||
| WBCnstr00036676 | |||||||||
| Antibody | WBAntibody00002718 | ||||||||
| WBAntibody00002719 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (156) | |||||||||
| Interaction | WBInteraction000285492 | ||||||||
| WBInteraction000375497 | |||||||||
| WBInteraction000404186 | |||||||||
| WBInteraction000408973 | |||||||||
| WBInteraction000438074 | |||||||||
| WBProcess | WBbiopr:00000055 | ||||||||
| Map_info | Map | X | Position | -3.37427 | Error | 0.03205 | |||
| Positive | Positive_clone | C14F11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4387 | |||||||
| 4420 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (44) | |||||||||
| Remark | [Hugh M Robertson].I've recognized five C. elegans genes as members of a large family of gustatory receptors (about 60 total) in the Drosophila genome originally described by John Carlson's laboratory. Phylogenetically they form three distinct lineages within this family, indicating that the family predates the nematode/arthropod split. In the absence of functional, mutant, or expression data, I prefer to name them in the least definitive manner possibl, but indicating that they are candidate receptors (seven-TM superfamily) related to the gustatory receptors of Drosophila. | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
