WormBase Tree Display for Gene: WBGene00001699
expand all nodes | collapse all nodes | view schema
| WBGene00001699 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Person_evidence | WBPerson83 | ||||||||
| SMap | S_parent | Sequence | F09D12 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | grd-10 | Person_evidence | WBPerson83 | |||||
| Sequence_name | F09D12.1 | ||||||||
| Molecular_name | F09D12.1 | ||||||||
| F09D12.1.1 | |||||||||
| CE16971 | |||||||||
| Other_name | CELE_F09D12.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | grd-10 | ||||||||
| DB_info | Database | AceView | gene | 4E207 | |||||
| WormQTL | gene | WBGene00001699 | |||||||
| WormFlux | gene | WBGene00001699 | |||||||
| NDB | locus_tag | CELE_F09D12.1 | |||||||
| NCBI | gene | 184239 | |||||||
| RefSeq | protein | NM_067946.5 | |||||||
| TrEMBL | UniProtAcc | O44471 | |||||||
| UniProt_GCRP | UniProtAcc | O44471 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | grd | ||||||||
| Allele (20) | |||||||||
| Strain | WBStrain00002426 | ||||||||
| WBStrain00002518 | |||||||||
| WBStrain00002935 | |||||||||
| WBStrain00032873 | |||||||||
| WBStrain00032904 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| Ortholog (17) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | grd-10 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; GRD-10 is expressed in seamcells; the Ground domain is predicted to form a cysteine-crosslinkedprotein involved in intercellular signalling, and it has subtlesimilarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-10is weakly required for normal molting; GRD-10 is also required fornormal growth to full size and locomotion; all of these requirements mayreflect common defects in cholesterol-dependent hedgehog-like signallingor in vesicle trafficking. | Paper_evidence | WBPaper00003717 | |||||
| WBPaper00006525 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Enriched in several structures, including ABalppppaa; PLM; germ line; non-striated muscle; and somatic nervous system based on Chronogram; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including nicotinic acid; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Ground-like domain. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F09D12.1 | |||||||
| Corresponding_transcript | F09D12.1.1 | ||||||||
| Other_sequence | JI218756.1 | ||||||||
| Associated_feature | WBsf645874 | ||||||||
| WBsf228101 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00044110 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00030704 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076999 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077023 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012968 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1226 | ||||||||
| Chronogram1444 | |||||||||
| Expr4435 | |||||||||
| Expr5697 | |||||||||
| Expr1016283 | |||||||||
| Expr1031014 | |||||||||
| Expr1148078 | |||||||||
| Expr2012224 | |||||||||
| Expr2030460 | |||||||||
| Drives_construct | WBCnstr00003037 | ||||||||
| WBCnstr00004510 | |||||||||
| WBCnstr00011998 | |||||||||
| WBCnstr00036757 | |||||||||
| Construct_product | WBCnstr00036757 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (266) | |||||||||
| Interaction | WBInteraction000309835 | ||||||||
| WBInteraction000324733 | |||||||||
| WBInteraction000424863 | |||||||||
| WBInteraction000553089 | |||||||||
| WBInteraction000561753 | |||||||||
| WBInteraction000572731 | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | IV | Position | -4.03129 | Error | 0.029423 | |||
| Positive | Positive_clone | F09D12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003717 | ||||||||
| WBPaper00026841 | |||||||||
| WBPaper00028754 | |||||||||
| WBPaper00031588 | |||||||||
| WBPaper00042648 | |||||||||
| WBPaper00061786 | |||||||||
| WBPaper00064105 | |||||||||
| WBPaper00065085 | |||||||||
| WBPaper00065833 | |||||||||
| Remark | grd-10 is paralogous to grd-5 | Paper_evidence | WBPaper00003717 | ||||||
| grd-3, grd-10, and grd-13 form a cluster, grd-3 and grd-13 are paralogous to the grd-4 and grd-14 cluster | Paper_evidence | WBPaper00003717 | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
