WormBase Tree Display for Gene: WBGene00001692
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| WBGene00001692 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | W05E7 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | grd-3 | Person_evidence | WBPerson83 | |||||
| Sequence_name | W05E7.1 | ||||||||
| Molecular_name | W05E7.1 | ||||||||
| W05E7.1.1 | |||||||||
| CE34103 | |||||||||
| Other_name | CELE_W05E7.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | grd-3 | ||||||||
| DB_info | Database | AceView | gene | 4E205 | |||||
| WormQTL | gene | WBGene00001692 | |||||||
| WormFlux | gene | WBGene00001692 | |||||||
| NDB | locus_tag | CELE_W05E7.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001692|UniProtKB=Q9TYW7 | |||||||
| family | PTHR46706 | ||||||||
| NCBI | gene | 177109 | |||||||
| RefSeq | protein | NM_067945.6 | |||||||
| TREEFAM | TREEFAM_ID | TF316923 | |||||||
| TrEMBL | UniProtAcc | Q9TYW7 | |||||||
| UniProt_GCRP | UniProtAcc | Q9TYW7 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | grd | ||||||||
| Allele (15) | |||||||||
| Strain | WBStrain00032786 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00097722 | ||||||||
| 00097723 | |||||||||
| 00097724 | |||||||||
| 00097725 | |||||||||
| Ortholog (19) | |||||||||
| Paralog (25) | |||||||||
| Structured_description | Concise_description | grd-3 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; GRD-3 is expressed in adultanterior and posterior seam cells, overlapping GRD-5 expression; GRD-3is also strongly expressed upon infection with the gram-negativebacterium Serratia marcescens, indicating that GRD-3 may be part of C.elegans' innate immunity response; the Ground domain is predicted toform a cysteine-crosslinked protein acting as an intercellular signal,and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOGproteins; GRD-3 is weakly required for normal molting; GRD-3 is alsorequired for normal growth to full size and locomotion; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00002823 | |||||
| WBPaper00003717 | |||||||||
| WBPaper00005382 | |||||||||
| WBPaper00005654 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable signaling receptor binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular region. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | W05E7.1 | |||||||
| Corresponding_CDS_history | W05E7.1:wp100 | ||||||||
| Corresponding_transcript | W05E7.1.1 | ||||||||
| Other_sequence | FD517194.1 | ||||||||
| CSC00396_1 | |||||||||
| CJC00964_1 | |||||||||
| CBC04410_1 | |||||||||
| FD514418.1 | |||||||||
| FD517785.1 | |||||||||
| CRC10049_1 | |||||||||
| FD517127.1 | |||||||||
| CSC00396_2 | |||||||||
| Associated_feature | WBsf645873 | ||||||||
| WBsf995962 | |||||||||
| WBsf995963 | |||||||||
| WBsf995964 | |||||||||
| WBsf228100 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00077017 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00103567 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00075992 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00054823 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00019622 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076992 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr635 | ||||||||
| Expr1966 | |||||||||
| Expr1029206 | |||||||||
| Expr1031010 | |||||||||
| Expr1158365 | |||||||||
| Expr2012233 | |||||||||
| Expr2030469 | |||||||||
| Drives_construct | WBCnstr00006286 | ||||||||
| WBCnstr00012459 | |||||||||
| WBCnstr00036764 | |||||||||
| Construct_product | WBCnstr00036764 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (300) | |||||||||
| Interaction | WBInteraction000309835 | ||||||||
| WBInteraction000310799 | |||||||||
| WBInteraction000416885 | |||||||||
| WBInteraction000519374 | |||||||||
| WBInteraction000549461 | |||||||||
| WBInteraction000549462 | |||||||||
| WBInteraction000574865 | |||||||||
| WBInteraction000585659 | |||||||||
| WBInteraction000586349 | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | IV | Position | -4.09953 | Error | 0.033813 | |||
| Positive | Positive_clone | W05E7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Y55H10 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003717 | ||||||||
| WBPaper00005382 | |||||||||
| WBPaper00011801 | |||||||||
| WBPaper00025183 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00028754 | |||||||||
| WBPaper00031588 | |||||||||
| WBPaper00061547 | |||||||||
| WBPaper00064105 | |||||||||
| Remark | yk66e9 spans only grd-3, which contains just ground domain. grd-3, grd-10, and grd-13 form a cluster, grd-3 and grd-13 are paralogous to the grd-4 and grd-14 cluster. | Paper_evidence | WBPaper00003717 | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
