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WormBase Tree Display for Gene: WBGene00001565

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Name Class

WBGene00001565EvidenceCGC_data_submission
SMapS_parentSequenceC14B9
IdentityVersion1
NameCGC_namegei-8Person_evidenceWBPerson1796
Sequence_nameC14B9.6
Molecular_nameC14B9.6a
C14B9.6a.1
CE42991
C14B9.6c
CE48463
C14B9.6c.1
Other_namepqn-12
CELE_C14B9.6Accession_evidenceNDBBX284603
Public_namegei-8
DB_infoDatabaseAceViewgene3J202
WormQTLgeneWBGene00001565
WormFluxgeneWBGene00001565
NDBlocus_tagCELE_C14B9.6
PanthergeneCAEEL|WormBase=WBGene00001565|UniProtKB=P34333
familyPTHR13992
NCBIgene176145
RefSeqproteinNM_171207.9
NM_066372.8
SwissProtUniProtAccP34333
UniProt_GCRPUniProtAccP34333
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgei
Allele (118)
StrainWBStrain00036421
WBStrain00036659
RNASeq_FPKM (74)
GO_annotation00041711
00041712
00041713
00041714
00041715
00041716
00041717
Ortholog (23)
Structured_descriptionConcise_descriptiongei-8 encodes a novel protein highly similar to C. briggsae BP:CBP04038 that contains a glutamine/asparagine (Q/N)-rich ('prion') domain (by the algorithm of Michelitsch and Weissman) and two myb-like DNA-binding domains; interacts with GEX-3 in yeast two-hybrid assays.Paper_evidenceWBPaper00005068
WBPaper00005194
WBPaper00012788
WBPaper00012830
WBPaper00012882
WBPaper00012897
WBPaper00013003
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including anal depressor muscle; egg-laying apparatus; germ line; somatic nervous system; and tail ganglion. Human ortholog(s) of this gene implicated in Huntington's disease. Is an ortholog of human NCOR1 (nuclear receptor corepressor 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:12858Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7672)
Molecular_infoCorresponding_CDSC14B9.6a
C14B9.6c
Corresponding_CDS_historyC14B9.6a:wp126
C14B9.6a:wp194
C14B9.6b:wp126
C14B9.6b:wp194
C14B9.6b:wp238
C14B9.6c:wp126
C14B9.6c:wp194
C14B9.6c:wp238
Corresponding_transcriptC14B9.6a.1
C14B9.6c.1
Other_sequenceCJC01035_1
Oden_isotig08996
Associated_featureWBsf667130
WBsf667131
WBsf667132
WBsf667133
WBsf717939
WBsf993243
WBsf993244
WBsf1015359
WBsf227081
Transcription_factorWBTranscriptionFactor000765
Experimental_infoRNAi_result (15)
Expr_patternExpr10782
Expr10783
Expr10784
Expr10785
Expr1021058
Expr1030935
Expr1144572
Expr2012017
Expr2030253
Drives_constructWBCnstr00017732
WBCnstr00017733
WBCnstr00017734
WBCnstr00036857
Construct_productWBCnstr00016611
WBCnstr00021812
WBCnstr00036857
Regulate_expr_clusterWBPaper00042128:gei-8(ok1671)_downregulated
WBPaper00042128:gei-8(ok1671)_upregulated
Microarray_results (37)
Expression_cluster (125)
Interaction (34)
Map_infoMapIIIPosition-0.376759Error0.000149
PositivePositive_cloneC14B9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkSequence connection from [Qadota H, Kaibuchi K]
The pqn-12 gene was merged into this gene following advice from [Hodgkin J]. gei-8 was previously attached to C14B9.5 but this sequence was then merged into C14B9.6 to create a splice variant and this change has led to the two gene names being merged. [020621 krb]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene