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WormBase Tree Display for Gene: WBGene00001394

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Name Class

WBGene00001394SMapS_parentSequenceW02A2
IdentityVersion1
NameCGC_namefat-2
Sequence_nameW02A2.1
Molecular_nameW02A2.1a
W02A2.1a.1
CE21231
W02A2.1b
CE49971
W02A2.1b.1
Other_nameCELE_W02A2.1Accession_evidenceNDBBX284604
Public_namefat-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfat
Allele (35)
StrainWBStrain00031679
WBStrain00004011
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (32)
ParalogWBGene00001393Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionfat-2 encodes a delta-12 fatty acyl desaturase that increases membranefluidity when expressed in yeast, and that may protect against coldstress; FAT-2's substrate is unknown, but may be acyl-CoA; FAT-2 isrequired in vivo for normal levels of C18 or C20 polyunsaturated fattyacids (PUFAs); FAT-2 is fully required for a sperm-attracting cue(perhaps an eicosanoid) secreted by oocytes, and partially required forthe polarizing activity of PAR-3, PAR-6, and other proteins; FAT-2 isalso required for a normally fast growth rate and movement rate, and fornormal body shape, defecation rhythm, and brood size; when expressed in yeast, FAT-2 exhibits a v+3 mode of desaturase activity, catalyzing double bond formation three carbons from an existing double bond.Paper_evidenceWBPaper00003999
WBPaper00005233
WBPaper00005728
WBPaper00013538
WBPaper00013550
WBPaper00024509
WBPaper00027724
WBPaper00028527
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated10 Jun 2010 00:00:00
Automated_descriptionEnables stearoyl-CoA 9-desaturase activity. Involved in several processes, including collagen and cuticulin-based cuticle development; fatty acid biosynthetic process; and innate immune response. Predicted to be located in membrane.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSW02A2.1a
W02A2.1b
Corresponding_transcriptW02A2.1a.1
W02A2.1b.1
Other_sequence (153)
Associated_featureWBsf660885
WBsf979037
WBsf998380
WBsf998381
WBsf1018513
WBsf229419
Experimental_infoRNAi_result (19)
Expr_patternChronogram1822
Expr6815
Expr1021921
Expr1030834
Expr1158089
Expr2011435
Expr2029673
Drives_constructWBCnstr00003419
WBCnstr00036975
Construct_productWBCnstr00036975
Microarray_results (19)
Expression_cluster (258)
Interaction (211)
WBProcessWBbiopr:00000121
Map_infoMapIVPosition8.52821Error0.001854
PositivePositive_cloneW02A2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4297
4298
Pseudo_map_position
Reference (56)
RemarkM03A8.1 link removed by agreement. [sdm 0107]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene