WormBase Tree Display for Gene: WBGene00001340
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| WBGene00001340 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | etr-1 | Person_evidence | WBPerson261 | |||||
| Sequence_name | T01D1.2 | ||||||||
| Molecular_name (70) | |||||||||
| Other_name | CELE_T01D1.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | etr-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | etr | ||||||||
| Allele (130) | |||||||||
| Possibly_affected_by | WBVar02152955 | ||||||||
| WBVar02152954 | |||||||||
| Strain | WBStrain00054854 | ||||||||
| WBStrain00054853 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (43) | |||||||||
| Paralog (13) | |||||||||
| Structured_description | Concise_description | etr-1 encodes a muscle-specific ELAV-type RNA-binding protein, whose homologs include Drosophila ELAV and human CUG-BINDING PROTEIN (CUGBP1; OMIM:601074); etr-1 function is required for embryonic muscle development, which suggests that ETR-1's homology to CUG-BP (implicated in myotonic dystrophy) might reflect conserved roles in development. | Paper_evidence | WBPaper00003747 | |||||
| WBPaper00005068 | |||||||||
| WBPaper00012788 | |||||||||
| WBPaper00012830 | |||||||||
| WBPaper00012882 | |||||||||
| WBPaper00012897 | |||||||||
| WBPaper00013003 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable mRNA 3'-UTR binding activity. Involved in determination of adult lifespan. Located in nucleus. Expressed in body wall musculature; cloacal sphincter muscle; copulatory spicule; non-striated muscle; and somatic gonad. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 97. Is an ortholog of human CELF1 (CUGBP Elav-like family member 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070383 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2550) | ||||
| Molecular_info | Corresponding_CDS (19) | ||||||||
| Corresponding_CDS_history | T01D1.2b:wp182 | ||||||||
| T01D1.2c:wp247 | |||||||||
| Corresponding_transcript (32) | |||||||||
| Other_sequence (57) | |||||||||
| Associated_feature (19) | |||||||||
| Experimental_info | RNAi_result (25) | ||||||||
| Expr_pattern | Expr1204 | ||||||||
| Expr9488 | |||||||||
| Expr13464 | |||||||||
| Expr1026122 | |||||||||
| Expr1030819 | |||||||||
| Expr1155747 | |||||||||
| Expr2011378 | |||||||||
| Expr2029614 | |||||||||
| Drives_construct | WBCnstr00010149 | ||||||||
| WBCnstr00036992 | |||||||||
| Construct_product | WBCnstr00014053 | ||||||||
| WBCnstr00036992 | |||||||||
| Regulate_expr_cluster | WBPaper00062325:etr-1(lq61)_downregulated | ||||||||
| WBPaper00062325:etr-1(lq61)_upregulated | |||||||||
| WBPaper00062325:muscle_depleted_coding-RNA | |||||||||
| WBPaper00062325:muscle_depleted_noncoding-RNA | |||||||||
| WBPaper00062325:muscle_enriched_coding-RNA | |||||||||
| WBPaper00062325:muscle_enriched_noncoding-RNA | |||||||||
| Antibody | WBAntibody00002767 | ||||||||
| Microarray_results (74) | |||||||||
| Expression_cluster (115) | |||||||||
| Interaction (42) | |||||||||
| Map_info | Map | II | Position | -15.9026 | Error | 0.013546 | |||
| Positive | Positive_clone | T01D1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (23) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
