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WormBase Tree Display for Gene: WBGene00001085

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Name Class

WBGene00001085SMapS_parentSequenceC25G4
IdentityVersion1
NameCGC_namedpy-26Person_evidenceWBPerson261
Sequence_nameC25G4.5
Molecular_nameC25G4.5
C25G4.5.1
CE08398
Other_nameCELE_C25G4.5Accession_evidenceNDBBX284604
Public_namedpy-26
DB_infoDatabaseAceViewgene4N212
WormQTLgeneWBGene00001085
WormFluxgeneWBGene00001085
NDBlocus_tagCELE_C25G4.5
NCBIgene178196
RefSeqproteinNM_069977.9
SwissProtUniProtAccG5EGE9
TREEFAMTREEFAM_IDTF317844
UniProt_GCRPUniProtAccG5EGE9
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdpy
Reference_alleleWBVar00089317
Allele (97)
Legacy_informationn199mat : XX daughters of n199/+ mothers are maternally rescued weak dumpy phenotype with protruding vulva (ES2) 4% Him; XX daughters of n199/n199 mothers are severely dumpy and Him (2% of brood) or die as embryos or young larvae (98% of XX brood). XO n199 animals are non-dumpy almost wildtype males (ME3). Similar or slightly stronger phenotypes in n199/Df. NA3 (n198 (resembles n199) y6 (weaker phenotypes).
See also n198, n199, y6
[C.elegansII] n199mat : XX daughters of n199/+ mothers are maternally rescued weak dumpy phenotype with protruding vulva (ES2) 4% Him; XX daughters of n199/n199 mothers are severely dumpy and Him (2% of brood) or die as embryos or young larvae (98% of XX brood). XO n199 animals are non-dumpy almost wildtype males (ME3). Similar or slightly stronger phenotypes in n199/Df. OA3: n198 (resembles n199), y6 (weaker phenotypes), y65. Cloned: encodes predicted 1263 aa novel protein; antibody staining indicates DPY-26 associated with X chromosomes in XX, diffuse nuclear in XO. [Plenefisch et al. 1989; TY]
StrainWBStrain00004455
WBStrain00004613
WBStrain00004619
WBStrain00004623
WBStrain00034748
WBStrain00054695
RNASeq_FPKM (74)
GO_annotation (15)
Contained_in_operonCEOP4516
Ortholog (18)
Structured_descriptionConcise_descriptiondpy-26 encodes a novel, acidic protein that is highly conserved in other Caenorhabditis species; during development, dpy-26 activity is required for both dosage compensation and meiotic chromosome segregation; DPY-26 localizes to all meiotic chromosomes in the germline and to the hermaphrodite X chromosomes in somatic cells; SDC-1, SDC-2, and SDC-3 proteins form a complex and these three proteins, in turn, colocalize with DPY-26, DPY-27, and MIX-1 proteins both on the X chromosome and on a transgenic her-1(+) array.Paper_evidenceWBPaper00002605
WBPaper00002606
WBPaper00005215
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated21 May 2007 00:00:00
Automated_descriptionInvolved in dosage compensation by hypoactivation of X chromosome; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Located in condensed nuclear chromosome. Part of dosage compensation complex. Expressed widely.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC25G4.5
Corresponding_transcriptC25G4.5.1
Other_sequenceU43562
CBC04037_1
CR05839
CRC11903_1
PPC12755_1
CBC13777_1
CBC01161_1
CRC07128_1
Associated_featureWBsf652298
WBsf668431
WBsf231021
WBsf231022
WBsf231023
Experimental_infoRNAi_resultWBRNAi00041214Inferred_automaticallyRNAi_primary
WBRNAi00011181Inferred_automaticallyRNAi_primary
WBRNAi00080293Inferred_automaticallyRNAi_primary
WBRNAi00080269Inferred_automaticallyRNAi_primary
WBRNAi00080286Inferred_automaticallyRNAi_primary
WBRNAi00080273Inferred_automaticallyRNAi_primary
WBRNAi00080282Inferred_automaticallyRNAi_primary
Expr_patternExpr1570
Expr9851
Expr1022687
Expr1030690
Expr1145250
Expr1200198
Expr2011067
Expr2029304
Drives_constructWBCnstr00037090
Construct_productWBCnstr00037090
AntibodyWBAntibody00000131
WBAntibody00000807
WBAntibody00000808
WBAntibody00001591
WBAntibody00001964
WBAntibody00002034
WBAntibody00002040
WBAntibody00002734
Microarray_results (23)
Expression_cluster (104)
Interaction (86)
WBProcessWBbiopr:00000056
WBbiopr:00000099
Map_infoMapIVPosition5.94177Error0.00601
Well_ordered
PositivePositive_cloneC25G4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point648
819
823
824
Multi_point568
569
570
764
765
766
767
1916
5281
Landmark_gene
Reference (112)
MethodGene