WormBase Tree Display for Gene: WBGene00000895
expand all nodes | collapse all nodes | view schema
| WBGene00000895 | SMap | S_parent | Sequence | B0412 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dac-1 | Person_evidence | WBPerson473 | |||||
| Sequence_name | B0412.1 | ||||||||
| Molecular_name | B0412.1a | ||||||||
| B0412.1a.1 | |||||||||
| CE26848 | |||||||||
| B0412.1b | |||||||||
| CE33550 | |||||||||
| B0412.1b.1 | |||||||||
| Other_name | ski-1 | Person_evidence | WBPerson473 | ||||||
| CELE_B0412.1 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | dac-1 | ||||||||
| DB_info | Database | AceView | gene | 3B439 | |||||
| WormQTL | gene | WBGene00000895 | |||||||
| WormFlux | gene | WBGene00000895 | |||||||
| NDB | locus_tag | CELE_B0412.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000895|UniProtKB=H2KY91 | |||||||
| family | PTHR12577 | ||||||||
| NCBI | gene | 175238 | |||||||
| RefSeq | protein | NM_001025959.5 | |||||||
| NM_001025958.4 | |||||||||
| SwissProt | UniProtAcc | H2KY91 | |||||||
| TREEFAM | TREEFAM_ID | TF316697 | |||||||
| UniProt_GCRP | UniProtAcc | H2KY91 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dac | ||||||||
| Allele (159) | |||||||||
| Strain | WBStrain00001324 | ||||||||
| WBStrain00001325 | |||||||||
| WBStrain00035649 | |||||||||
| WBStrain00035733 | |||||||||
| WBStrain00035736 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00021457 | ||||||||
| 00021458 | |||||||||
| 00021459 | |||||||||
| 00021460 | |||||||||
| 00021461 | |||||||||
| 00021462 | |||||||||
| 00021463 | |||||||||
| 00021464 | |||||||||
| 00021465 | |||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | dac-1 encodes the C. elegans ortholog of Dachshund, a transcriptional regulator first described in Drosophila that is a member of the SKI/SNO/DAC family of proteins; dac-1 is expressed at higher levels in the AFD thermosensory neurons as compared to the AWB olfactory neurons and likely plays a role in thermosensory behavior as on thermal gradients dac-1 mutants fail to suppress cryophilic drive but continue to track isotherms at the cultivation temperature; a DAC-1::GFP fusion protein is nuclear and expressed strongly in the AFD thermosensory neurons, but weakly in the AWC, ASE, and ASK chemosensory neurons; expression is also seen in alae and additional, unidentified tail cells; dac-1 expression in AFD is positively regulated by the TTX-1 OTX-like homeodomain protein. | Paper_evidence | WBPaper00024671 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 21 May 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in thermotaxis. Located in nucleus. Expressed in amphid neurons; cuticular ala; and tail. Is an ortholog of human DACH1 (dachshund family transcription factor 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | B0412.1a | |||||||
| B0412.1b | |||||||||
| Corresponding_CDS_history | B0412.1b:wp120 | ||||||||
| B0412.1b:wp123 | |||||||||
| Corresponding_transcript | B0412.1a.1 | ||||||||
| B0412.1b.1 | |||||||||
| Other_sequence | Dviv_isotig11489 | ||||||||
| SSC00720_1 | |||||||||
| Dviv_isotig11488 | |||||||||
| SS02097 | |||||||||
| Associated_feature | WBsf658584 | ||||||||
| WBsf978943 | |||||||||
| WBsf224400 | |||||||||
| Transcription_factor | WBTranscriptionFactor000635 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00028128 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00009756 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006647 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00110961 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00039031 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram2070 | ||||||||
| Expr3130 | |||||||||
| Expr5066 | |||||||||
| Expr7403 | |||||||||
| Expr1015167 | |||||||||
| Expr1143193 | |||||||||
| Expr1200045 | |||||||||
| Expr2010758 | |||||||||
| Expr2028995 | |||||||||
| Drives_construct | WBCnstr00002217 | ||||||||
| WBCnstr00002218 | |||||||||
| WBCnstr00011158 | |||||||||
| WBCnstr00012546 | |||||||||
| WBCnstr00037214 | |||||||||
| Construct_product | WBCnstr00011158 | ||||||||
| WBCnstr00016702 | |||||||||
| WBCnstr00037214 | |||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (120) | |||||||||
| Interaction (95) | |||||||||
| WBProcess | WBbiopr:00000010 | ||||||||
| Map_info | Map | III | Position | -25.7793 | Error | 0.003862 | |||
| Positive | Positive_clone | B0412 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4251 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00010874 | ||||||||
| WBPaper00024524 | |||||||||
| WBPaper00024671 | |||||||||
| WBPaper00026952 | |||||||||
| WBPaper00027309 | |||||||||
| WBPaper00033137 | |||||||||
| WBPaper00034843 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00065158 | |||||||||
| Remark | ski-1 became an other-name of dac-1 as this locus encodes the C. elegans ortholog of Dachshund, rather than of the related protein SKI | Person_evidence | WBPerson473 | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
