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WormBase Tree Display for Gene: WBGene00000882

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Name Class

WBGene00000882SMapS_parentSequenceF42G9
IdentityVersion2
NameCGC_namecyn-6Person_evidenceWBPerson466
Sequence_nameF42G9.2
Molecular_nameF42G9.2
F42G9.2.1
CE01301
Other_namecyp-6Person_evidenceWBPerson466
CELE_F42G9.2Accession_evidenceNDBBX284603
Public_namecyn-6
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
220 Sep 2004 16:20:03WBPerson1971Name_changeCGC_namecyp-6 -> cyn-6
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyn
Allele (14)
Legacy_information[C.elegansII] NMK. Cyclophilin family. Signal peptide. Cosmid C51B6. [TP]
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (35)
Paralog (18)
Structured_descriptionConcise_descriptioncyn-6 encodes a cyclophilin most similar to human secreted cyclophilin type B isoforms that is functional when expressed in E. coli; it is expressed in the intestine.Paper_evidenceWBPaper00002472
WBPaper00005482
WBPaper00026884
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated20 Mar 2007 00:00:00
Automated_descriptionPredicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is an ortholog of human PPIB (peptidylprolyl isomerase B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110349Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9255)
Molecular_infoCorresponding_CDSF42G9.2
Corresponding_transcriptF42G9.2.1
Other_sequence (76)
Associated_featureWBsf654939
WBsf658581
Experimental_infoRNAi_resultWBRNAi00076416Inferred_automaticallyRNAi_primary
WBRNAi00027816Inferred_automaticallyRNAi_primary
WBRNAi00014849Inferred_automaticallyRNAi_primary
WBRNAi00006569Inferred_automaticallyRNAi_primary
WBRNAi00047133Inferred_automaticallyRNAi_primary
WBRNAi00022707Inferred_automaticallyRNAi_primary
WBRNAi00090595Inferred_automaticallyRNAi_primary
WBRNAi00022708Inferred_automaticallyRNAi_primary
Expr_patternExpr1991
Expr1024208
Expr1030547
Expr1151001
Expr2010674
Expr2028914
Drives_constructWBCnstr00010563
WBCnstr00037224
Construct_productWBCnstr00010563
WBCnstr00037224
Microarray_results (19)
Expression_cluster (222)
SAGE_tag (15)
Interaction (142)
Map_infoMapIIIPosition-26.1239Error0.022372
PositivePositive_cloneC51B6Author_evidencePage AM
F42G9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00002472
WBPaper00005482
WBPaper00015191
WBPaper00024704
WBPaper00026884
WBPaper00033090
WBPaper00038491
WBPaper00055090
WBPaper00065331
Remarksignal_peptide
[Page AM] Initially identified by the sequencing project. Referred to as cypB homolog by Blast analysis. cDNA clone isolated
PPIase or cyclophilin, EC 5.2.1.8
This gene has been renamed with approval of the CGC (cyp-6->cyn-6)Person_evidenceWBPerson466
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene