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WormBase Tree Display for Gene: WBGene00000524

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Name Class

WBGene00000524SMapS_parentSequenceZK563
IdentityVersion1
NameCGC_nameclc-3
Sequence_nameZK563.4
Molecular_nameZK563.4a
ZK563.4a.1
CE05095
ZK563.4b
CE33749
ZK563.4b.1
Other_nameCELE_ZK563.4Accession_evidenceNDBBX284606
Public_nameclc-3
DB_infoDatabaseAceViewgeneXD992
WormQTLgeneWBGene00000524
WormFluxgeneWBGene00000524
NDBlocus_tagCELE_ZK563.4
NCBIgene180625
RefSeqproteinNM_001029822.7
NM_001029823.6
TrEMBLUniProtAccH2KYF7
Q23532
UniProt_GCRPUniProtAccQ23532
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classclc
Allele (19)
StrainWBStrain00032092
RNASeq_FPKM (74)
GO_annotation00021548
00021549
00021550
00021551
00078776
00107534
Ortholog (22)
Structured_descriptionConcise_descriptionclc-3 encodes a claudin homolog that may regulate ion channels; CLC-3 is worm-specific, with a highly divergent sequence weakly similar to mammalian voltage-dependent calcium channel gamma subunits that are known or suspected to prevent epilepsy in vivo (e.g., stargazin; MGI:1316660); claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.Paper_evidenceWBPaper00004961
WBPaper00005946
WBPaper00005975
WBPaper00012762
WBPaper00012856
WBPaper00012941
WBPaper00013626
WBPaper00018356
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be involved in epithelial cell-cell adhesion. Located in plasma membrane.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK563.4a
ZK563.4b
Corresponding_transcriptZK563.4a.1
ZK563.4b.1
Other_sequenceCBC06882_1
Associated_featureWBsf653835
WBsf1004605
WBsf237168
WBsf237169
WBsf237170
Experimental_infoRNAi_resultWBRNAi00038341Inferred_automaticallyRNAi_primary
WBRNAi00059519Inferred_automaticallyRNAi_primary
WBRNAi00081187Inferred_automaticallyRNAi_primary
WBRNAi00022064Inferred_automaticallyRNAi_primary
Expr_patternExpr9465
Expr1011435
Expr1162936
Expr2010043
Expr2028284
Drives_constructWBCnstr00037475
Construct_productWBCnstr00014030
WBCnstr00037475
Microarray_results (22)
Expression_cluster (109)
InteractionWBInteraction000133970
WBInteraction000136804
WBInteraction000140913
WBInteraction000314375
WBInteraction000349867
WBInteraction000444156
Map_infoMapXPosition-10.3996Error0.020116
PositivePositive_cloneZK563Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4219
Pseudo_map_position
ReferenceWBPaper00005946
WBPaper00013424
WBPaper00013425
WBPaper00018356
WBPaper00023962
WBPaper00026406
WBPaper00034662
WBPaper00038444
WBPaper00039831
WBPaper00044402
RemarkSequence connection from [Asano A, Tsukita S]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene