WormBase Tree Display for Gene: WBGene00000482
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| WBGene00000482 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | chd-3 | Person_evidence | WBPerson8 | |||||
| Sequence_name | T14G8.1 | ||||||||
| Molecular_name | T14G8.1 | ||||||||
| T14G8.1.1 | |||||||||
| CE03657 | |||||||||
| Other_name | CELE_T14G8.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | chd-3 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | chd | ||||||||
| Allele (121) | |||||||||
| Strain | WBStrain00032145 | ||||||||
| WBStrain00008565 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (36) | |||||||||
| Ortholog (44) | |||||||||
| Paralog (19) | |||||||||
| Structured_description | Concise_description | chd-3 encodes a PHD-finger SNF2 family member containing a chromo domain and a C-terminal helicase domain that affects Notch-dependent vulval development; expressed in virtually all embryonic cells and in many larval nuclei. | Paper_evidence | WBPaper00004171 | |||||
| WBPaper00004491 | |||||||||
| WBPaper00018132 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent activity, acting on DNA; and chromatin binding activity. Involved in cell fate determination; negative regulation of Ras protein signal transduction; and negative regulation of vulval development. Predicted to be located in nucleus. Predicted to be part of NuRD complex. Expressed in several structures, including distal tip cell; pharynx; ventral nerve cord; vulva; and vulval precursor cell. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and lymphoma. Is an ortholog of human CHD3 (chromodomain helicase DNA binding protein 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1919) | ||||
| DOID:1993 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1919) | ||||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1919) | ||||||
| DOID:1324 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1919) | ||||||
| DOID:234 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1919) | ||||||
| DOID:0060058 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1919) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16816,HGNC:1919) | ||||||
| Molecular_info | Corresponding_CDS | T14G8.1 | |||||||
| Corresponding_transcript | T14G8.1.1 | ||||||||
| Other_sequence (39) | |||||||||
| Associated_feature | WBsf655713 | ||||||||
| WBsf671155 | |||||||||
| WBsf671156 | |||||||||
| WBsf671157 | |||||||||
| WBsf1007448 | |||||||||
| WBsf1024138 | |||||||||
| WBsf238087 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00018728 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00053345 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00075564 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00070008 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00081570 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113476 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035580 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1044 | ||||||||
| Expr9223 | |||||||||
| Expr1020503 | |||||||||
| Expr1030284 | |||||||||
| Expr1156930 | |||||||||
| Expr2009956 | |||||||||
| Expr2028196 | |||||||||
| Drives_construct | WBCnstr00010045 | ||||||||
| WBCnstr00013809 | |||||||||
| WBCnstr00037504 | |||||||||
| WBCnstr00038090 | |||||||||
| Construct_product | WBCnstr00037504 | ||||||||
| WBCnstr00038090 | |||||||||
| Regulate_expr_cluster | WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo | ||||||||
| WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo | |||||||||
| WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo | |||||||||
| WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo | |||||||||
| WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo | |||||||||
| WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo | |||||||||
| WBPaper00050163:chd-3(eh4)_upregulated_24-cell-embryo | |||||||||
| WBPaper00050163:chd-3(eh4)_upregulated_100-cell-embryo | |||||||||
| Antibody | WBAntibody00002259 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (184) | |||||||||
| Interaction (66) | |||||||||
| Map_info | Map | X | Position | 8.51882 | Error | 0.073253 | |||
| Positive | Positive_clone | T14G8 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4215 | |||||||
| 4883 | |||||||||
| 5508 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (38) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
