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WormBase Tree Display for Gene: WBGene00000302

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Name Class

WBGene00000302SMapS_parentSequenceC56A3
IdentityVersion1
NameCGC_namecav-2Person_evidenceWBPerson464
Sequence_nameC56A3.7
Molecular_name (12)
Other_nameCELE_C56A3.7Accession_evidenceNDBBX284605
Public_namecav-2
DB_infoDatabaseAceViewgene5O39
WormQTLgeneWBGene00000302
WormFluxgeneWBGene00000302
NDBlocus_tagCELE_C56A3.7
PanthergeneCAEEL|WormBase=WBGene00000302|UniProtKB=Q18879
familyPTHR10844
NCBIgene179838
RefSeqproteinNM_001269596.3
NM_001269595.3
NM_001269594.3
NM_001269597.3
SwissProtUniProtAccQ18879
TREEFAMTREEFAM_IDTF315736
UniProt_GCRPUniProtAccQ18879
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcav
Allele (89)
Legacy_informationNo mutants known. Encodes predicted 261aa protein, 28% identical to cav-1. Residues 214-351 have 24% identity to mammalian caveolins. 2.4 kb transcript detected. Predicted gene C56A3.7
StrainWBStrain00000430
WBStrain00003572
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (25)
ParalogWBGene00000301Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptioncav-2 encodes one of two C. elegans proteins related to caveolins, integral transmembrane proteins that are believed to function in regulation of signal transduction and that are the major component of caveolae, specialized lipid rafts found in the plasma membrane of most cell types; as loss of cav-2 function via large-scale RNA-mediated interference (RNAi) screens does not result in any obvious abnormalities, the role of cav-2 in C. elegans development and/or behavior is not yet known; cav-2 mRNA is expressed in eggs and mixed stage populations.Paper_evidenceWBPaper00002653
WBPaper00003590
WBPaper00005654
Curator_confirmedWBPerson1843
WBPerson324
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables lipid transporter activity. Involved in parturition and regulation of egg-laying behavior. Located in apical plasma membrane.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC56A3.7a
C56A3.7b
C56A3.7c
C56A3.7d
Corresponding_transcriptC56A3.7a.1
C56A3.7b.1
C56A3.7c.1
C56A3.7d.1
Other_sequence (12)
Associated_featureWBsf647464
WBsf1001843
WBsf1001844
WBsf232786
WBsf232787
Experimental_infoRNAi_resultWBRNAi00043257Inferred_automaticallyRNAi_primary
WBRNAi00102916Inferred_automaticallyRNAi_primary
WBRNAi00102917Inferred_automaticallyRNAi_primary
WBRNAi00102909Inferred_automaticallyRNAi_primary
WBRNAi00027704Inferred_automaticallyRNAi_primary
WBRNAi00012452Inferred_automaticallyRNAi_primary
WBRNAi00102915Inferred_automaticallyRNAi_primary
WBRNAi00102910Inferred_automaticallyRNAi_primary
Expr_patternChronogram499
Expr2724
Expr5596
Expr12158
Expr1020786
Expr1030193
Expr1147237
Expr2009737
Expr2027977
Drives_constructWBCnstr00004024
WBCnstr00020296
WBCnstr00020297
WBCnstr00020479
WBCnstr00037594
Construct_productWBCnstr00020296
WBCnstr00020479
WBCnstr00020480
WBCnstr00037594
AntibodyWBAntibody00002615
Microarray_results (22)
Expression_cluster (179)
Interaction (14)
Map_infoMapVPosition5.45137Error0.007118
PositivePositive_cloneC56A3Person_evidenceWBPerson464
Author_evidenceTang Z
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4176
4324
Pseudo_map_position
ReferenceWBPaper00002653
WBPaper00003590
WBPaper00004384
WBPaper00006323
WBPaper00024791
WBPaper00027612
WBPaper00028448
WBPaper00035456
WBPaper00046406
WBPaper00055090
RemarkData extracted from Tang et al. (1997)
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene