WormBase Tree Display for Analysis: Microarray_Study.WBPaper00048762.ce.mr
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| Microarray_Study.WBPaper00048762.ce.mr | DB_info | Database | GEO | GSE73070 |
|---|---|---|---|---|
| Title | RIP-Chip analysis of the C. elegans FOG-1 and FOG-3 proteins | |||
| Description | FOG-1/CPEB and FOG-3/Tob are the terminal regulators of the sex determination in C. elegans germ cells. CPEB and Tob proteins are both translational regulators. To investigate how FOG-1 and FOG-3 regulate germ cell sex determination we sought to identify the target mRNAs. We used transgenic epitope tagged animals (3xMyc::FOG-1 and FOG-3::3xFLAG). To identify the mRNA targets of FOG-1/CPEB and FOG-3/Tob on a genome wide scale we used RNA immunoprecipitation followed by microarray analysis. We found 81 putative mRNA targets of FOG-1 and 722 putative targets of FOG-3. 76 target mRNAs were common to both FOG-1 and FOG-3. | |||
| Category | physical interaction | |||
| Microarray_experiment (40) | ||||
| Species_in_analysis | Caenorhabditis elegans | |||
| Reference | WBPaper00048762 |
