- YOP1
Saccharomyces cerevisiae Reticulon-interacting protein; ER integral membrane protein involved in the generation of tubular ER morphology; promotes membrane curvature; forms tubules in vitro; regulates the ER asymmetry-induced inheritance block during ER stress; role in ER-derived peroxisomal biogenesis; interacts with Yip1p to mediate membrane traffic and with Sey1p to maintain ER morphology; facilitates lipid exchange between the ER and mitochondria; forms ER foci upon DNA replication stress
- RTN1
Saccharomyces cerevisiae Reticulon protein; involved in nuclear pore assembly and maintenance of tubular ER morphology; promotes membrane curvature; regulates the ER asymmetry-induced inheritance block during ER stress; role in ER-derived peroxisomal biogenesis; increases tubular ER when overexpressed; mutants have reduced phosphatidylserine transfer between the ER and mitochondria; interacts with exocyst subunit Sec6p, Yip3p, and Sbh1p; member of the RTNLA subfamily
- TIP20
Saccharomyces cerevisiae Peripheral membrane protein required for COPI vesicle fusion to the ER; mediates Sey1p-independent homotypic ER fusion; prohibits back-fusion of COPII vesicles with the ER; forms a tethering complex with Sec39p and Dsl1p that interacts with ER SNAREs Sec20p and Use1p
- SLY41
Saccharomyces cerevisiae Protein involved in ER-to-Golgi transport; packaged into COPII vesicles for trafficking between ER and Golgi
- ERV2
Saccharomyces cerevisiae Flavin-linked sulfhydryl oxidase localized to the ER lumen; involved in disulfide bond formation within the endoplasmic reticulum (ER)
- KDELR1
Homo sapiens ER lumen protein retaining receptor 1
- YPR063C
Saccharomyces cerevisiae ER-localized protein of unknown function
- EPS1
Saccharomyces cerevisiae ER protein with chaperone and co-chaperone activity; involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family
- MAY24
Saccharomyces cerevisiae Peripheral ER membrane protein; putative ER chaperone required for the stability and function of nutrient permeases exposed to high pressure
- SEC39
Saccharomyces cerevisiae Component of the Dsl1p tethering complex; this complex interacts with ER SNAREs Sec20p and Use1p; mediates Sey1p-independent homotypic ER fusion; proposed to be involved in protein secretion; localizes to the ER and nuclear envelope