Figure 6 Localization of LET-805::GFP knock-ins. In late-stage embryos from (A) wild-type, (B)
let805(ju1123), and (C) larval animals,LET-805::GFP localizes to epidermal attachment structures overlying body wall muscles and (D) tothe uterine seam. In embryos, LET805::GFP localization in
let-805suppressor mutant backgroundsresembled that of the wild-typeLET-805::GFP; in adults mutantfor suppressor alleles
let-805(
ju1123),
let-805(
ju1165), and
let805(ju1184), LET-805::GFP displays increased aggregates alongthe mid-body (E) (arrowheads). (F)Quantitation of aggregation as described in Materials and Methods;significance, t-test, ** P , 0.01,*** P , 0.001.