Picture from Cho, Jaehyoung et al. MicroPubl Biol
Figure 1 (A) Network diagram showing a map of C. elegans protein-protein interactions. This cluster includes 17,990 unique protein-protein interactions from 6,079 protein coding genes in the C. elegans genome. This map was generated by Cytoscape 3.6.1. (B) Comparisons of the curation status between the major databases for C. elegans protein-protein interaction data. As of September 2018, IMEx has 16,443 total and 12,433 unique protein-protein interactions with 4,967 unique genes annotated from 253 papers. BioGRID has 6,274 total and 5,734 unique protein-protein interactions with 3,212 unique genes annotated from 174 papers. In contrast, WormBase has 28,279 total and 17,990 unique protein-protein interactions with 6,079 unique genes annotated from 1,251 papers. The inserted bar-graph shows the number of unique genes curated for the protein-protein interactions in each database. (C) Statistics of the experimental evidence types curated for the protein interaction data set in WormBase. The experimental evidence type for each protein interaction is annotated as described in the BioGRID curation guide for 'physical experimental systems' (https://wiki.thebiogrid.org/doku.php/curation_guide:biochemical_experimental_systems). However, in WormBase, "Colocalization" is annotated as an evidence type only when the interaction is supported by other detection methods. Within the total 18,734 yeast two-hybrid interactions, 17,312 interactions come from large-scale, high-throughput studies and 1,422 come from small-scale studies.
Picture from Meissner B et al. (2011) PLoS One "Determining the sub-cellular localization of proteins within Caenorhabditis ...."
Figure 7. Sub-cellular localization patterns for some category 13 and 14 GFP-tagged proteins. Panels A, B and C show single symmetrical, spindle-shaped body wall muscle cells exhibiting GFP-tagged protein localization. Panels D and E show two adjacent body wall muscle cells exhibiting GFP-tagged protein localization. The category 13 protein, F47F2.1, (A), localizes to the cytoplasm or cytosol. The four category 14 proteins exhibit unique and unusual localization patterns. The D2092.4 protein (B) localizes to organized dots associated with the myofilament lattice. The R11G1.6 protein (C) localizes to ridges and dots in the muscle cell membrane. The K06A4.3 protein (D) appears to localize to the actin cytoskeleton and dense bodies. The F42C5.9 protein (E) is present in the cell membrane, as well as filament-like structures and dense body-like structures. Bars represent 10 um.