Picture from Nguyen TQ et al. (2000) J Cell Sci "The C. elegans septin genes, unc-59 and unc-61, are required for normal ...."
Fig. 6. The distribution of UNC-59 and UNC-61 in the cleavage furrow and the midbody region.(A-F) illustrate that UNC-59 co-localizes with the actomyosin contractile ring. (A-C) A single embryo with the cleavage furrow about three-quarters ingressed; (D-F) a single embryo with the cleavage furrow fully ingressed. (A and D) Actin; (B and E) UNC-59;(C and F) merged images. (G-L) Embryos were double- labeled with non-muscle myosin II (NMY II)(red) and UNC-61 antibodies (green). The rows show the same embryo taken at the same focal plane. Similar to NMY-II (G), UNC-61 localizes to the leading edge of the cleavage furrow (H). The image (I) is a merged image of the NMY-II and UNC-61. At the terminal phase of cell division, both NMY-II (J) and UNC-61 (K) co-localizes to the midbody region. The image (L) is a merged image of J and K. Bar, 10 um.