Figure 1. The
odd-1(
tm848) mutation and its effect on brood size: A) The 989 bp wild-type
odd-1 transcript codes for a 242 amino acid (a.a.) protein and contains two exons (white boxes), the second of which contains three zinc finger domains (gray boxes). The
odd-1(
tm848) mutation deletes most of both exons and all of the zinc fingers, and inserts one codon, resulting in a 183 bp transcript (including the stop codon) and a 60 a.a. protein. B) The brood sizes for five
odd-1(+) and
odd-1(
tm848) worms were observed in three different experiments (a total of 15 worms were averaged for each strain). Each circle represents the brood size of an individual worm. The average is indicated on the plot by a horizontal black line. The numbers at the top of each sample group indicate the average offspring ± the standard deviation. P = 0.65 (2-tailed t-test with equal variance).