Figure 1. Muv penetrance, % induction and polymorphism mapping of Cbr-lin
(bh1) and Cbr-lin
(bh3):A. Muv penetrance was examined at 15
x2103;, 20
x2103; and 25
x2103;. Statistical test was carried out using one-way ANOVA with Bonferroni's multiple comparisons test (n= 40-50 from a total of 3 batches for each genotype and temperature). Muv penetrance for Cbr-lin
(bh1): 18% +/- 2% (15
x2103;), 27% +/- 3% (20
x2103;), and 41% +/- 3% (25
x2103;); and for Cbr-lin
(bh3): 38% +/- 3% (15
x2103;), 38% +/- 2% (20
x2103;), and 40% +/- 4% (25
x2103;). Asterisk (*) indicate statistically significant p values (*: p < 0.05, **: p < 0.01, ***: p < 0.001). B. VPC induction pattern of Cbr-lin
(bh1) and Cbr-lin
(bh3) animals at 20
x2103;. C. Cbr-lin
(bh1) showed linkage to the indel cb-
m6 but not to cb-
m142, suggesting its location on the right arm of chromosome I. Cbr-lin
(bh3) was linked to cb-
m205 but not to cb-
m46 and bdP1, which placed the gene roughly to the middle of chromosome III. The physical locations of the markers are in parentheses.