Figure 6. HMP-1 protein localization during elongation in wild-type and
hmp-2 mutant embryos. Labeling of dorsal and lateral hypodermal cells as in Fig. 3. (A) HMP-1 protein (red) in hypodermal cells of a wild-type elongating embryo at the 1.5 stage. (B) mAbMH27 staining (green) of hypodermal adherens junctions in the same embryo as in A. (C) Combined images of A and B showing the overlapping staining pattern in yellow. (D) Internal focal plane of a wild-type embryo as in A, revealing HMP-1 at adherens junctions of the pharynx (anterior to arrowheads), intestine (posterior to arrowheads), and the ventral midline (arrow). HMP-1 is also expressed in neurons of the nerve ring during neuronal differentiation (data not shown).