Figure 2. paqr gene expression and
paqr-2 tail tip phenotype. (A-C) Transgenic worms carrying the indicated transcriptional reporters are shown. Labels stand for the following: pg (pharyngeal gland), exc (excretory canal), gs (gonad sheath), vm (vulva muscle), int (intestine), hm (head muscle), amp (amphid neuron), nr (nerve ring), tn (tail neuron), hyp (hypodermis), rg (rectal gland) and thyp (tail hypodermis).
paqr-1P::GFP and
paqr-3P::GFP carry 1.5 kb of promoter while
paqr-3bP::GFP carry 3 kb of promoter. Control hermaphrodites have smooth tails extending over 200 um beyond the rectum (D) while
paqr-2 mutant hermaphrodites exhibits a withered tail tip phenotype (E) with a penetrance of 100%. Scales represent 50 um.