- neuronal sheath cell development variant
Any variation in the progression of a neuronal sheath cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A neuronal sheath cell is a structural cell that forms a specialized environment surrounding the sensory endings of a neuron.
- neurite development variant
Variations in the progression of a neuronal extension (such as axons or dendrites) over time, from its formation to the mature structure compared to control.
- neuron number variant
The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals.
- neuron positioning variant
The placement of neuronal cells, as a whole or of a specific class of neuron in the animal, deviates from that observed in control animals.
- synaptic vesicle exocytosis variant
Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control.
- dendrite development variant
Any variation in the processes that influence the generation of neuronal extensions, that carry afferent (incoming) action potentials towards the cell body compared to control.
- excess neurite outgrowth
Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated.
- neurite morphology variant
Animals display variations in the structure, organization of components, or spatial pattern of any projection stemming from a neuronal cell, compared to that observed in control animals.