Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C.
Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background.
Animals die during the final stages of embryogenesis. In C. elegans, this lethality refers to death during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation.