[
Japanese Worm Meeting,
2000]
Protein kinases are well known to play important roles, such as cell-cycle controls, apoptosis and stress responses. A lot of genes containing protein kinase domain are identified in the genome of C. elegans. However, the biological functions of their majority are still unknown. In order to isolate novel kinases involved in meiosis and gametogenasis, at first, we selected about 100 putative kinase genes in the genome. Their expression level were examined by RT-PCR reaction with total RNA from young adult and L2 larval hermaphrodite. After that, some genes whose expression levels obviously increased in young adults were investigated by the RNA interference method. As a result, we found that T08D2.7 is required for gametogenesis. In this presentation, we will discuss the results of functions of some protein kinases.