-
[
Cell Cycle,
2011]
Comment on: Banerjee D, et al. Cell Cycle 2010; 9:4748-65.
-
[
Neuromuscul Disord,
2004]
In her commentary on our recently published paper, A. de Luca questions the approach consisting in screening random molecules on a dystrophin-deficient invertebrate model (C. elegans) in order to identify potential therapeutic clues.
-
[
Curr Biol,
2013]
A century ago, Bridges proposed that male genes on the autosomes and female genes on the X chromosome compete to determine sexual identity. New genetic and molecular studies establish Caenorhabditis elegans as the first animal known to use this mechanism.
-
[
Nature,
1994]
On page 32 of this issue, a joint team from the Genome Sequencing Center (St. Louis, USA) and the newly founded Sanger Centre (Hinxton Hall, Cambridge, UK) report a contiguous sequence of over two megabases from chromosome III of the nematode worm, Caenorhabditis elegans. This is the longest contiguous DNA sequence yet determined, and it prompts rumination on how far we have come in the sequencing enterprise, and on how far - and where - we have
-
[
Elife,
2016]
The regeneration of axons relies on a previously unknown mechanism that involves the regulation of alternative splicing by CELF proteins.
-
[
Curr Biol,
2011]
Recent work on a Caenorhabditis elegans transmembrane ATPase reveals a central role for the aminophospholipid phosphatidylethanolamine in the production of a class of extracellular vesicles.
-
[
Nature,
1997]
Who scapes the lurking sepent's mortal sting? Not he that sets his foot upon her back. Even the smallest of worms will turn, when trodden on.
-
[
Science,
1998]
The near completion of the sequence of the C. elegans genome should provide researchers with a gold mine of information on topics ranging from evolution to gene
-
[
Dev Cell,
2009]
Cell invasion through the basement membrane, a process important for both development and disease pathogenesis, depends on an interplay of adhesive, force transducing, proteolytic, and chemotactic machineries. The mechanisms whereby these different processes are integrated on the cellular level have remained elusive. In this issue of Developmental Cell, Sherwood and coworkers now identify integrins as integration platforms for a specialized invasive membrane domain in C. elegans.
-
[
Nature,
2002]
Behavioral ecologists have shown that many animals form social groups in conditions. Neurobiological evidence for this behaviour has now been discovered in the nematode worm, Caenorhabditis elegans. On pages 899 and 925 of this issue, de Bono et al. and Coates and de Bono present striking results on the genetic, molecular and neural mechanisms underlying nematode social feeding. These discoveries provide tantalizing insights into the effects of stress in social groupings.